Tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate
CAS No.:710973-92-5
Molecular Formula:C14H26N2O2
Molecular Weight:254.373
Hs Code.:
European Community (EC) Number:878-319-7
Mol file:710973-92-5.mol

Synonyms:tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate;710973-92-5;tert-butyl 4-[(cyclopropylMethyl)aMino]piperidine-1-;tert-butyl 4-(cyclopropylmethylamino)piperidine-1-carboxylate;SCHEMBL4658038;ZAYYQFFOEAGSRB-UHFFFAOYSA-N;4-[(Cyclopropylmethyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;EN300-89949;tert-butyl4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate;4-(Cyclopropylmethyl-amino)-piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of Tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate

Chemical Property:

PSA：41.57000
LogP:2.71430
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:254.199428076
Heavy Atom Count:18
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)NCC2CC2

Technology Process of Tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate

There total 2 articles about Tert-butyl 4-[(cyclopropylmethyl)amino]piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 2516-47-4
cyclopropanemethylamine

: 710973-92-5
4-(cyclopropylmethylamino)piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; for 1h; under 2068.65 Torr;

Reference yield:

: 710973-92-5
4-(cyclopropylmethylamino)piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:

Reference yield: 82.2%

: 710973-92-5
4-(cyclopropylmethylamino)piperidine-1-carboxylic acid tert-butyl ester

: 90176-80-0
2-(trifluoromethyl)-4-fluorobenzaldehyde

: 4-[cyclopropylmethyl-(4-fluoro-2-trifluoromethyl-benzyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 4-(cyclopropylmethylamino)piperidine-1-carboxylic acid tert-butyl ester; 2-(trifluoromethyl)-4-fluorobenzaldehyde; With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 22.5 - 27.3 ℃; for 8h;

2-(trifluoromethyl)-4-fluorobenzaldehyde; With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 22.5 ℃; for 23h;

2-(trifluoromethyl)-4-fluorobenzaldehyde; With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 23 ℃; for 24h;