16alpha,17-Epoxy-3beta-hydroxy-5alpha-pregnan-20-one

Base Information

Chemical Name:16alpha,17-Epoxy-3beta-hydroxy-5alpha-pregnan-20-one
CAS No.:1097-50-3
Molecular Formula:C₂₁H₃₂O₃
Molecular Weight:332.483
Hs Code.:
DSSTox Substance ID:DTXSID90911297
Mol file:1097-50-3.mol

Synonyms:16 alpha,17-epoxy-3 beta-hydroxy-5 alpha-pregnan-20-one;16,17-EHPO;5-pregnene-3beta-ol-16,17-epoxi-20-one

Suppliers and Price of 16alpha,17-Epoxy-3beta-hydroxy-5alpha-pregnan-20-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 16alpha,17-Epoxy-3beta-hydroxy-5alpha-pregnan-20-one

Chemical Property:

Vapor Pressure:5.89E-10mmHg at 25°C
Boiling Point:449.2°Cat760mmHg
Flash Point:152.8°C
PSA：0.00000
Density:1.158g/cm³
LogP:0.00000
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:332.23514488
Heavy Atom Count:24
Complexity:588

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C12C(O1)CC3C2(CCC4C3CCC5C4(CCC(C5)O)C)C
Isomeric SMILES:CC(=O)[C@]12C(O1)C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC[C@@H]5[C@@]4(CC[C@@H](C5)O)C)C

Technology Process of 16alpha,17-Epoxy-3beta-hydroxy-5alpha-pregnan-20-one

There total 7 articles about 16alpha,17-Epoxy-3beta-hydroxy-5alpha-pregnan-20-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: (3β,16α)-16,17-epoxy-3-hydroxypregn-5-en-20-one

: 1044-90-2,1097-50-3,74015-78-4,95044-31-8,113563-82-9
(3β,5α,16α)-16,17-epoxy-3-hydroxypregnan-20-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; for 1.5h; Inert atmosphere;
DOI:10.1021/jm300317k

Reference yield:

: 1044-90-2,1097-50-3,74015-78-4,95044-31-8,113563-82-9
(3β,5α,16α)-16,17-epoxy-3-hydroxypregnan-20-one

Guidance literature:: With sodium hydroxide;
DOI:10.1021/ja01254a506

Reference yield:

: 1169-20-6
3β-acetoxy-5α-pregn-16-en-20-one

: 1044-90-2,1097-50-3,74015-78-4,95044-31-8,113563-82-9
(3β,5α,16α)-16,17-epoxy-3-hydroxypregnan-20-one

Guidance literature:: With methanol; sodium hydroxide; dihydrogen peroxide; Erwaermen des Reaktionsprodukts mit wss.-methanol. Kaliumcarbonat-Loesung oder wss.-methanol. Kaliumhydrogencarbonat-Loesung;
DOI:10.1002/hlca.19580410622