N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide

Base Information

• Chemical Name: N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide
• CAS No.: 123152-43-2
• Molecular Formula: C₄₆H₆₅N₅O₉
• Molecular Weight: 832.05
• Mol file: 123152-43-2.mol

Synonyms:

Chemical Property of N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide

There total 5 articles about N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide (123152-42-1) → N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide (123152-43-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 2h; Yield given; Ambient temperature;

DOI:10.1021/jo00284a044

Reference yield:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-cyanobutyl)-N-(phenylmethoxy)butanediamide (112139-65-8) → N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide (123152-43-2)

Guidance literature:

Multi-step reaction with 5 steps

1: HCl (gas) / 20 h / -20 °C

2: H₂O / 6 h / 0 °C

3: 55 percent / aq. KOH / acetone / Ambient temperature

4: dicyclohexylcarbodiimide (DCC), (dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

5: NaBH₄ / ethanol / 2 h / Ambient temperature

With hydrogenchloride; dmap; potassium hydroxide; sodium tetrahydroborate; water; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; acetone;

DOI:10.1021/jo00284a044

Reference yield:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-carboxybutyl)-N-(phenylmethoxy)butanediamide (123152-41-0) → N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide (123152-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexylcarbodiimide (DCC), (dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

2: NaBH₄ / ethanol / 2 h / Ambient temperature

With dmap; sodium tetrahydroborate; dicyclohexyl-carbodiimide; In ethanol; dichloromethane;

DOI:10.1021/jo00284a044

upstream raw materials:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-cyanobutyl)-N-(phenylmethoxy)butanediamide

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-carboxybutyl)-N-(phenylmethoxy)butanediamide

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-(ethoxycarbonyl)butyl)-N-(phenylmethoxy)butanediamide