(S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

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Chemical Name:(S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester
CAS No.:192067-29-1
Molecular Formula:C₃₂H₄₇N₇O₇
Molecular Weight:641.768
Hs Code.:

(S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

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Technology Process of (S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

There total 3 articles about (S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: H-Arg-OPr

: 192067-28-0
(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionic acid ethyl ester

: 192067-29-1
(S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

Guidance literature:: at -25 ℃; chymotrypsin, 0.025 M borate buffer, pH 9.0;
DOI:10.1002/anie.199710991

Reference yield:

: 949-67-7
L-tyrosine ethyl ester

: 192067-29-1
(S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / 25 °C / clostripain, 0.025 M borate buffer, pH 8.0

2: 84 percent / -25 °C / chymotrypsin, 0.025 M borate buffer, pH 9.0

DOI:10.1002/anie.199710991

Reference yield:

: 69861-90-1
Nα-benzyloxycarbonyl-L-lysine thiobenzyl ester

: 192067-29-1
(S)-2-[(S)-2-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / 25 °C / clostripain, 0.025 M borate buffer, pH 8.0

2: 84 percent / -25 °C / chymotrypsin, 0.025 M borate buffer, pH 9.0

DOI:10.1002/anie.199710991