(S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Base Information

Chemical Name:(S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester
CAS No.:202348-52-5
Molecular Formula:C₄₃H₅₀N₆O₁₄
Molecular Weight:874.902
Hs Code.:

(S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Synonyms:

Suppliers and Price of (S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

There total 5 articles about (S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 209604-82-0
3-aminomethyl-5-nitrobenzoic acid methyl ester

: 202348-52-5
(S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: LiOH / tetrahydrofuran

2: DCC, N-hydroxysuccimimide

3: DCC, N-hydroxysuccimimide

With lithium hydroxide; 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In tetrahydrofuran;
DOI:10.1002/anie.199726801

Reference yield:

: 50826-00-1
5-nitroisophthalamic acid methyl ester

: 202348-52-5
(S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: BH₃

2: LiOH / tetrahydrofuran

3: DCC, N-hydroxysuccimimide

4: DCC, N-hydroxysuccimimide

With lithium hydroxide; 1-hydroxy-pyrrolidine-2,5-dione; borane; dicyclohexyl-carbodiimide; In tetrahydrofuran;
DOI:10.1002/anie.199726801

Reference yield:

: 71989-14-5
Fmoc-(tBu)Asp-OH

: 202348-52-5
(S)-N-[3-({[(S)-2-tert-Butoxycarbonyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-5-nitro-benzyl]-3-(9H-fluoren-9-ylmethoxycarbonylamino)-succinamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: DCC, N-hydroxysuccimimide

2: DCC, N-hydroxysuccimimide

With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide;
DOI:10.1002/anie.199726801