(2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester

Base Information

• Chemical Name: (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester
• CAS No.: 99285-19-5
• Molecular Formula: C₃₆H₅₄O₁₃
• Molecular Weight: 694.817

Synonyms:

Chemical Property of (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester

There total 12 articles about (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R,3S,4S,5R,6R,8R,10R)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-2,4,6,8-tetramethyl-9-oxo-undecanoic acid methyl ester (99300-11-5) → (2R,3S,4S,5R,6R,8R,9R,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester (99285-19-5,99340-66-6) + (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester (99285-19-5,99340-66-6)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 25 ℃; for 1.5h; Yield given. Yields of byproduct given;

DOI:10.1139/v85-470

Reference yield:

(2R,3S,4S,5R,6R,8R,10R)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-2,4,6,8-tetramethyl-9-oxo-undecanoic acid methyl ester (99300-11-5) → (2R,3S,4S,5R,6R,8R,9R,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester (99285-19-5,99340-66-6) + (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester (99285-19-5,99340-66-6)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 25 ℃; for 1.5h; Yield given. Yields of byproduct given;

DOI:10.1139/v85-470

Reference yield:

(2R,3S,4S)-3-Acetoxy-4-((2R,3R,5R,6R)-6-{(S)-1-[(4S,5S)-5-(1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-ethyl}-3-benzyloxy-6-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-yl)-2-methyl-pentanoic acid methyl ester (99285-18-4) → (2R,3S,4S,5R,6R,8R,9R,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester (99285-19-5,99340-66-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / triethylamine / various solvent(s) / 20 h / 25 °C

2: NaBH₄ / methanol; tetrahydrofuran / 1.5 h / 25 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; methanol;

DOI:10.1139/v85-470

upstream raw materials:

(2R,3S,4S,5R,6R,8R,10R)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-2,4,6,8-tetramethyl-9-oxo-undecanoic acid methyl ester

(2R,3S,4S)-3-Acetoxy-4-((2R,3R,5R,6R)-6-{(S)-1-[(4S,5S)-5-(1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-ethyl}-3-benzyloxy-6-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-yl)-2-methyl-pentanoic acid methyl ester

(2R,3S,4S)-4-((2R,3R,5R,6R,8S,9R,10S,11S)-3-Benzyloxy-8-ethyl-9,10-dihydroxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-2-yl)-3-hydroxy-2-methyl-pentanoic acid methyl ester

C₃₀H₄₄O₉

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 99285-19-5 (2R,3S,4S,5R,6R,8R,9S,10S)-3,5-Diacetoxy-10-[(4R,5R)-5-((R)-1-acetoxy-propyl)-5-methyl-2-oxo-[1,3]dioxolan-4-yl]-6-benzyloxy-9-hydroxy-2,4,6,8-tetramethyl-undecanoic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send