2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine

Base Information

• Chemical Name: 2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine
• CAS No.: 157031-44-2
• Molecular Formula: C₃₉H₂₉N₅O₇
• Molecular Weight: 679.689
• Mol file: 157031-44-2.mol

Synonyms:

Chemical Property of 2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine

There total 1 articles about 2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzoyl chloride (98-88-4) + (desoxy-3-methylidene-3'-β-D-erythro-pentofurannosyl)-9-adenine (78151-96-9) → 2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine (157031-44-2)

Guidance literature:

With pyridine;

DOI:10.1016/S0040-4039(00)73206-0

Reference yield: 95.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine (157031-44-2) → C40H31N7O7

Guidance literature:

In diethyl ether; dichloromethane; for 48h; Ambient temperature;

DOI:10.1016/S0040-4039(00)73206-0

Reference yield:

2',5',N,N-tetrabenzoyl-3'-deoxy-3'-methyleneadenosine (157031-44-2) → 2',5',N,N-tetrabenzoyl-3'-deoxyadenosine-3'-spirocyclopropane

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / diethyl ether; CH₂Cl₂ / 48 h / Ambient temperature

2: benzophenone / acetonitrile; benzene / Irradiation

benzophenone; In diethyl ether; dichloromethane; acetonitrile; benzene;

DOI:10.1016/S0040-4039(00)73206-0

upstream raw materials:

benzoyl chloride

(desoxy-3-methylidene-3'-β-D-erythro-pentofurannosyl)-9-adenine