5-phosphono-2-pyrrolidone

Base Information

• Chemical Name: 5-phosphono-2-pyrrolidone
• CAS No.: 102394-14-9
• Molecular Formula: C₄H₈NO₄P
• Molecular Weight: 165.086
• Mol file: 102394-14-9.mol

Synonyms:

Chemical Property of 5-phosphono-2-pyrrolidone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-phosphono-2-pyrrolidone

There total 1 articles about 5-phosphono-2-pyrrolidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 4-oxobutanoate (10138-10-0) → 4-amino-4-phosphonobutanoic acid (18865-31-1) + 5-phosphono-2-pyrrolidone (102394-14-9)

Guidance literature:

With hydrogenchloride; O-benzyl carbamate; acetic acid; phosphorus trichloride; Yield given. Multistep reaction; 1.) reflux, 30 min, 2.) reflux, 0.5 h;

DOI:10.1007/BF00814338

Reference yield: 72.0%

5-phosphono-2-pyrrolidone (102394-14-9) → 4-amino-4-phosphonobutanoic acid (18865-31-1)

Guidance literature:

With hydrogenchloride; for 8h; Heating;

DOI:10.1007/BF00814338

upstream raw materials:

ethyl 4-oxobutanoate

Downstream raw materials:

4-amino-4-phosphonobutanoic acid