1,2,3,6,7,9a-Hexahydro-4H-quinolizine

Base Information

• Chemical Name: 1,2,3,6,7,9a-Hexahydro-4H-quinolizine
• CAS No.: 1004-90-6
• Molecular Formula: C₉H₁₅N
• Molecular Weight: 137.225
• Mol file: 1004-90-6.mol

Synonyms:1,2,3,4,5,6,7,9a-octahydro-quinolizine;2H-Quinolizine,1,3,4,6,7,9a-hexahydro;1,3,4,6,7,9a-Hexahydro-2H-quinolizine;1,3,4,6,7,9a-Hexahydro-2H-chinolizin;(+-)-1,3,4,6,7,9a-hexahydro-2H-quinolizin;

Chemical Property of 1,2,3,6,7,9a-Hexahydro-4H-quinolizine

Chemical Property:

• PSA: 3.24000
• LogP: 1.73870

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,3,6,7,9a-Hexahydro-4H-quinolizine

There total 4 articles about 1,2,3,6,7,9a-Hexahydro-4H-quinolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-acetoxy-octahydro-quinolizine (17943-26-9) → (+/-)-1,3,4,6,7,9a-Hexahydro-2H-chinolizin (1004-90-6)

Guidance literature:

at 535 ℃;

DOI:10.1021/ja01607a064

Reference yield:

octahydro-2H-quinolizin-1-ylamine (80220-52-6) → (+)-1,3,4,6,7,9a-hexahydro-2H-quinolizin (1004-90-6)

Guidance literature:

With hydrogenchloride; sodium nitrite; Anschliessendes Behandeln mit wss. Kalilauge und Erwaermen des Reaktionsprodukts;

Reference yield:

(1R,9aR)-1-aminooctahydro-1H-quinolizine (80220-52-6,98482-32-7,98482-33-8) → norlupinene (1004-90-6)

Guidance literature:

With hydrogenchloride; sodium nitrite;

upstream raw materials:

(1R,9aR)-1-aminooctahydro-1H-quinolizine

1-acetoxy-octahydro-quinolizine

octahydro-2H-quinolizin-1-ylamine