octahydro-1H-quinolizin-1-amine

Base Information

Chemical Name:octahydro-1H-quinolizin-1-amine
CAS No.:80220-52-6
Molecular Formula:C9H18N2
Molecular Weight:154.255
Hs Code.:
European Community (EC) Number:864-826-0
DSSTox Substance ID:DTXSID00543548

Synonyms:octahydro-1H-quinolizin-1-amine;80220-52-6;2H-Quinolizin-1-amine, octahydro-;2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-amine;SCHEMBL1697382;Octahydro-2H-quinolizin-1-amine;DTXSID00543548;octahydro-2h-quinolizin-1-ylamine;AKOS022635307;CS-0224255;EN300-118496;G55915

Suppliers and Price of octahydro-1H-quinolizin-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of octahydro-1H-quinolizin-1-amine

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:154.146998583
Heavy Atom Count:11
Complexity:136

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN2CCCC(C2C1)N

Technology Process of octahydro-1H-quinolizin-1-amine

There total 45 articles about octahydro-1H-quinolizin-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1421762-23-3
(1R,9aR)-octahydro-1-(di-tert-butyloxycarbonylamino)-1H-quinolizine

: 80220-52-6,98482-32-7,98482-33-8
(1R,9aR)-1-aminooctahydro-1H-quinolizine

Guidance literature:: With hydrogenchloride; In methanol; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.tetlet.2012.12.073

Reference yield:

: (1R,10R)-1-benzyloxycarbonylamino-7,8-didehydroquinolizidine

: 80220-52-6,98482-32-7,98482-33-8
(1R,9aR)-1-aminooctahydro-1H-quinolizine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/ol061736p

Reference yield:

: (2R,3R)-2-allyl-3-benzyloxycarbonylaminopiperidine

: 80220-52-6,98482-32-7,98482-33-8
(1R,9aR)-1-aminooctahydro-1H-quinolizine

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / acetonitrile / 34 h / 20 °C

2: Grubbs' second-generation catalyst / CH₂Cl₂ / 7 h / Heating

3: H₂ / Pd/C / ethanol

With hydrogen; potassium carbonate; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; palladium on activated charcoal; In ethanol; dichloromethane; acetonitrile;
DOI:10.1021/ol061736p