N-(2-(9H-carbazol-1-yl)phenyl)acetamide

Base Information

• Chemical Name: N-(2-(9H-carbazol-1-yl)phenyl)acetamide
• CAS No.: 2143475-98-1
• Molecular Formula: C₂₀H₁₆N₂O
• Molecular Weight: 300.36
• Mol file: 2143475-98-1.mol

Synonyms:

Chemical Property of N-(2-(9H-carbazol-1-yl)phenyl)acetamide

Chemical Property:

• Boiling Point: 568.3±25.0 °C(Predicted)
• Density: 1.281±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

GeA-69 >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-(9H-carbazol-1-yl)phenyl)acetamide

There total 2 articles about N-(2-(9H-carbazol-1-yl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-acetamidophenylboronic acid (169760-16-1) + 1-bromo-9H-carbazole (16807-11-7) → N-(2-(9H-carbazol-1-yl)phenyl)acetamide (2143475-98-1)

Guidance literature:

2-acetamidophenylboronic acid; 1-bromo-9H-carbazole; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,2-dimethoxyethane; In ethanol; at 20 ℃; for 0.166667h; Inert atmosphere;

With sodium carbonate; In ethanol; at 70 ℃; under 4500.45 Torr; Microwave irradiation; Inert atmosphere;

DOI:10.1021/acschembio.7b00445

Reference yield: 35.0%

N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (380430-61-5) + 1-bromo-9H-carbazole (16807-11-7) → N-(2-(9H-carbazol-1-yl)phenyl)acetamide (2143475-98-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; ethanol; water; at 90 ℃; for 2h; Inert atmosphere; Microwave irradiation;

DOI:10.1016/j.bmc.2018.03.020

Reference yield: 96.0%

N-(2-(9H-carbazol-1-yl)phenyl)acetamide (2143475-98-1) → 2-(9H-carbazol-1-yl)-N-ethylaniline

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; toluene; at 0 ℃; for 4.25h; Reflux;

DOI:10.1016/j.bmc.2018.03.020

upstream raw materials:

2-acetamidophenylboronic acid

1-bromo-9H-carbazole

N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide