[(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Base Information

Chemical Name:[(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane
CAS No.:189195-77-5
Molecular Formula:C₂₈H₄₇BrO₅Si
Molecular Weight:571.668
Hs Code.:

[(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Synonyms:

Suppliers and Price of [(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of [(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

There total 4 articles about [(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34591-97-4
3-(benzyloxy)propanal dimethyl acetal

: 189195-77-5
[(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 4 steps

1: camphorsulfonic acid / CH₂Cl₂

2: 1.) BF₃*OEt₂, acetic acid, 2.) 4-dimethylaminopyridine, triethylamine / 1.) cyclohexane, 23 deg C

3: 1.) (DHQD)2-PYR, OsO₄, K₃Fe(CN)6

With dmap; osmium(VIII) oxide; hydroquinindine-2,5-diphenyl-4,6-pyrimidinediyl diether; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; acetic acid; triethylamine; potassium hexacyanoferrate(III); In dichloromethane;
DOI:10.1021/jo970380f

Reference yield:

: 189195-74-2
(4R,6R)-4,6-Diallyl-2-(2-benzyloxy-ethyl)-[1,3]dioxane

: 189195-77-5
[(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BF₃*OEt₂, acetic acid, 2.) 4-dimethylaminopyridine, triethylamine / 1.) cyclohexane, 23 deg C

2: 1.) (DHQD)2-PYR, OsO₄, K₃Fe(CN)6

With dmap; osmium(VIII) oxide; hydroquinindine-2,5-diphenyl-4,6-pyrimidinediyl diether; boron trifluoride diethyl etherate; acetic acid; triethylamine; potassium hexacyanoferrate(III);
DOI:10.1021/jo970380f

Reference yield:

: 189195-75-3
Acetic acid (2S,4S,6R)-2-((R)-2-acetoxy-pent-4-enyl)-6-(2-benzyloxy-ethyl)-tetrahydro-pyran-4-yl ester

: 189195-77-5
[(2R,4S,6S)-2-(2-Benzyloxy-ethyl)-6-((4S,6R)-6-bromomethyl-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-tetrahydro-pyran-4-yloxy]-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) (DHQD)2-PYR, OsO₄, K₃Fe(CN)6

With osmium(VIII) oxide; hydroquinindine-2,5-diphenyl-4,6-pyrimidinediyl diether; potassium hexacyanoferrate(III);
DOI:10.1021/jo970380f