N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

Base Information

Chemical Name:N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt
CAS No.:949592-05-6
Molecular Formula:C₂HF₃O₂*C₃₉H₄₇ClFN₃O₂
Molecular Weight:758.296
Hs Code.:

N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

Synonyms:

Suppliers and Price of N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

There total 2 articles about N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 4.0%

: 4.4'-methylenebis(cyclohexylamine)

: 133-32-4
4-indol-3-yl-butyric acid

: 387-45-1
2-chloro-6-fluorobenzaldehyde

: 76-05-1
trifluoroacetic acid

: 949592-03-4
N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-(1H-indol-3-yl)butanamide trifluoroacetic acid salt

: 949592-05-6
N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

Guidance literature:: Multistep reaction.;
DOI:10.1016/j.bmc.2007.06.003

Reference yield:

: 133-32-4
4-indol-3-yl-butyric acid

: 76-05-1
trifluoroacetic acid

: 949592-03-4
N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-(1H-indol-3-yl)butanamide trifluoroacetic acid salt

: 949592-05-6
N-{4-[(4-aminocyclohexyl)methyl]cyclohexyl}-N-(2-chloro-6-fluorobenzyl)-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]butanamide trifluoroacetic acid salt

Guidance literature:: [{4-[(4-{[2-chloro-6-fluorobenzylidene]amino}cyclohexyl)methyl]cyclohexyl}aminocarbonyloxy](Wang resin); With sodium cyanoborohydride; acetic acid; trimethyl orthoformate; at 20 ℃; for 0.0833333h;

4-indol-3-yl-butyric acid; With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In dichloromethane; at 20 ℃; for 20h;

trifluoroacetic acid; With chlorotriisopropylsilane; ethane-1,2-dithiol; In water; at 20 ℃; for 1h; Further stages.;
DOI:10.1016/j.bmc.2007.06.003