2-AMINO-6-(4-METHYLPIPERAZINO)-3,5-PYRIDINEDICARBONITRILE

Base Information

• Chemical Name: 2-AMINO-6-(4-METHYLPIPERAZINO)-3,5-PYRIDINEDICARBONITRILE
• CAS No.: 154124-65-9
• Molecular Formula: C₁₂H₁₄N₆
• Molecular Weight: 242.283
• Mol file: 154124-65-9.mol

Synonyms:

Chemical Property of 2-AMINO-6-(4-METHYLPIPERAZINO)-3,5-PYRIDINEDICARBONITRILE

Chemical Property:

• Boiling Point: 485.6±45.0 °C(Predicted)
• PKA: 6.63±0.42(Predicted)
• Density: 1.33±0.1 g/cm3(Predicted)

Purity/Quality:

95%-98% ^*data from raw suppliers

2-Amino-6-(4-methylpiperazino)-3,5-pyridinedicarbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-AMINO-6-(4-METHYLPIPERAZINO)-3,5-PYRIDINEDICARBONITRILE

There total 2 articles about 2-AMINO-6-(4-METHYLPIPERAZINO)-3,5-PYRIDINEDICARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-amino-3-(4-methylpiperazino)propenenitrile (141536-41-6) + Ethoxymethylenemalononitrile (123-06-8) → 2-Amino-6-(4-methyl-piperazin-1-yl)-pyridine-3,5-dicarbonitrile (154124-65-9)

Guidance literature:

In ethanol; for 4h; Heating;

DOI:10.1002/jhet.5570300143

Reference yield:

3-amino-3-(4-methylpiperazino)propenenitrile (141536-41-6) → 2-Amino-6-(4-methyl-piperazin-1-yl)-pyridine-3,5-dicarbonitrile (154124-65-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / CHCl₃ / 24 h / 0 - 5 °C

2: 93 percent / ethanol / 2 h / Heating

In ethanol; chloroform;

DOI:10.1002/jhet.5570300143

upstream raw materials:

3-amino-3-(4-methylpiperazino)propenenitrile

Ethoxymethylenemalononitrile