11-formyl-4E,8E-undecadienoic acid

Base Information

• Chemical Name: 11-formyl-4E,8E-undecadienoic acid
• CAS No.: 55348-84-0
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.273
• Mol file: 55348-84-0.mol

Synonyms:

Chemical Property of 11-formyl-4E,8E-undecadienoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-formyl-4E,8E-undecadienoic acid

There total 2 articles about 11-formyl-4E,8E-undecadienoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z,Z,Z)-1,5,9-cyclodecatriene (16323-53-8) → (4Z,8Z)-12-Oxo-dodeca-4,8-dienoic acid (55348-84-0,55348-86-2)

Guidance literature:

With sodium acetate; acetic anhydride; ozone; acetic acid; Yield given. Multistep reaction; 1) glacial acetic acid, cyclohexane, 5 deg C; 2) 30 deg C, 1 h, 40 deg C, 30 min;

Reference yield:

(Z,Z,Z)-1,5,9-cyclododecatriene (4736-48-5) → (4Z,8Z)-12-Oxo-dodeca-4,8-dienoic acid (55348-84-0,55348-86-2)

Guidance literature:

With oxygen; sodium acetate; acetic anhydride; ozone; acetic acid; Multistep reaction; 1.) AcOH, cyclohexane, 5 deg C, 2.) from 30 to 40 deg C, 1.5 h;

Reference yield:

(4Z,8Z)-12-Oxo-dodeca-4,8-dienoic acid (55348-84-0,55348-86-2) → (7Z,11Z)-7,11-hexadecadien-1-yl acetate (52207-99-5)

Guidance literature:

Multi-step reaction with 10 steps

1: p-toluenesulfonic acid / 24 h / Ambient temperature

2: 90 percent / diisobutylaluminium hydride / diethyl ether; toluene / 1.5 h / -10 °C

3: 100 percent / pyridine / 20 h / 0 °C

4: 95 percent / 10percent aq. HCl / acetone / 6 h

5: 1.) Mg / 1.) THF, 2.) THF, RT, 3 h

6: pyridine / 20 h / 0 °C

7: NaI, Zn / tetrahydrofuran / 3 h / Heating

8: 95 percent / 10percent aq. HCl / acetone / 6 h / 40 °C

9: 95 percent / diisobutylaluminium hydride / diethyl ether; toluene / 1.5 h / -10 °C

10: 75 percent / pyridine

With pyridine; hydrogenchloride; diisobutylaluminium hydride; toluene-4-sulfonic acid; magnesium; sodium iodide; zinc; In tetrahydrofuran; diethyl ether; acetone; toluene;

upstream raw materials:

(Z,Z,Z)-1,5,9-cyclodecatriene

(Z,Z,Z)-1,5,9-cyclododecatriene

Downstream raw materials:

(7Z,11Z)-7,11-hexadecadien-1-yl acetate

Z,Z-7,11-hexadecadienyl alcohol

(4Z,8Z)-1,1-dimethoxy-12-tosyloxy-4,8-dodecadiene

1,1-ethylenedioxy-4-O-tosyloxy-7Z,11Z-hexadecadiene