1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

Base Information

Chemical Name:1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine
CAS No.:150916-80-6
Molecular Formula:C₃₃H₃₄Cl₂N₆O₄
Molecular Weight:649.577
Hs Code.:

1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<<cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl>methyleneoxy>phenyl>piperazine

Synonyms:

Suppliers and Price of 1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

There total 7 articles about 1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 43027-50-5
1,3-dimethyl-5-nitro-1,3-dihydro-2H-benzimidazol-2-one

: 150916-80-6
1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / ethanol / 3 h / 1810.02 Torr / Ambient temperature

2: 57 percent / N,N-dimethylcyclohexylamine / butan-1-ol / 5 h / Heating

3: 83 percent / 48percent aq. hydrobromic acid / 5 h / Heating

4: 1.) sodium hydride / 1.) DMF, RT, 20 min., 2.) DMF, 80-90 deg, 5 h

With N,N-dimethyl-cyclohexanamine; hydrogen bromide; hydrogen; sodium hydride; palladium on activated charcoal; In ethanol; butan-1-ol;
DOI:10.1002/jhet.5570290506

Reference yield:

: 53439-88-6
5-amino-1,3-dimethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one

: 150916-80-6
1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / N,N-dimethylcyclohexylamine / butan-1-ol / 5 h / Heating

2: 83 percent / 48percent aq. hydrobromic acid / 5 h / Heating

3: 1.) sodium hydride / 1.) DMF, RT, 20 min., 2.) DMF, 80-90 deg, 5 h

With N,N-dimethyl-cyclohexanamine; hydrogen bromide; sodium hydride; In butan-1-ol;
DOI:10.1002/jhet.5570290506

Reference yield:

: 19721-54-1
2-[(2-hydroxyethyl)-(4-methoxyphenyl)amino]ethanol

: 150916-80-6
1-<1,3-dimethyl-benzimidazol-2(3H)-on-5-yl>-4-<4-<methyleneoxy>phenyl>piperazine

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / phosphorus oxychloride / 0.5 h / 90 °C

2: 57 percent / N,N-dimethylcyclohexylamine / butan-1-ol / 5 h / Heating

3: 83 percent / 48percent aq. hydrobromic acid / 5 h / Heating

4: 1.) sodium hydride / 1.) DMF, RT, 20 min., 2.) DMF, 80-90 deg, 5 h

With N,N-dimethyl-cyclohexanamine; hydrogen bromide; sodium hydride; trichlorophosphate; In butan-1-ol;
DOI:10.1002/jhet.5570290506