2-(3-Chlorophenyl)-8-methyl-4-quinolinecarboxylic acid

Base Information

Chemical Name:2-(3-Chlorophenyl)-8-methyl-4-quinolinecarboxylic acid
CAS No.:107027-40-7
Molecular Formula:C₁₇H₁₂ClNO₂
Molecular Weight:297.741
Hs Code.:
DSSTox Substance ID:DTXSID301210550
Mol file:107027-40-7.mol

Synonyms:2-(3-chlorophenyl)-8-methyl-4-quinolinecarboxylic acid;2-(3-chlorophenyl)-8-methylquinoline-4-carboxylic acid;107027-40-7;4-Quinolinecarboxylic acid, 2-(3-chlorophenyl)-8-methyl-;Oprea1_576643;AK-968/41171842;DTXSID301210550;STK449393;AKOS002671935

Suppliers and Price of 2-(3-Chlorophenyl)-8-methyl-4-quinolinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(3-CHLOROPHENYL)-8-METHYL-4-QUINOLINECARBOXYLIC ACID 95.00%
5MG
$ 498.11

Total 0 raw suppliers

Chemical Property of 2-(3-Chlorophenyl)-8-methyl-4-quinolinecarboxylic acid

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:297.0556563
Heavy Atom Count:21
Complexity:389

Purity/Quality:: 2-(3-CHLOROPHENYL)-8-METHYL-4-QUINOLINECARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)C(=CC(=N2)C3=CC(=CC=C3)Cl)C(=O)O

Technology Process of 2-(3-Chlorophenyl)-8-methyl-4-quinolinecarboxylic acid

There total 1 articles about 2-(3-Chlorophenyl)-8-methyl-4-quinolinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1127-59-9
7-methyl-1H-indole-2,3-dione

: 99-02-5
3'-Chloroacetophenone

: 107027-40-7
2-(3-Chloro-phenyl)-8-methyl-quinoline-4-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; Heating;
DOI:10.1021/jm00122a018

Reference yield:

: 107027-40-7
2-(3-Chloro-phenyl)-8-methyl-quinoline-4-carboxylic acid

: 107027-52-1
2-(3-Chloro-phenyl)-8-methyl-quinoline

Guidance literature:: With copper; at 280 - 290 ℃;
DOI:10.1021/jm00122a018

Reference yield:

: 107027-40-7
2-(3-Chloro-phenyl)-8-methyl-quinoline-4-carboxylic acid

: 107027-65-6
2-(3-Chloro-phenyl)-quinoline-8-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Cu powder / 280 - 290 °C

2: CrO₃, conc. H₂SO₄ / H₂O / 90 - 105 °C

With chromium(VI) oxide; sulfuric acid; copper; In water;
DOI:10.1021/jm00122a018