8-bromo-3-methyl-7-(2-oxo-2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione

Base Information

• Chemical Name: 8-bromo-3-methyl-7-(2-oxo-2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione
• CAS No.: 101072-04-2
• Molecular Formula: C14H11BrN4O3
• Molecular Weight: 363.17
• Mol file: 101072-04-2.mol

Synonyms:8-Bromo-3-methyl-7-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione;7-phenacyl-8-bromo-3-methylxanthine;8-bromo-3,7-dihydro-3-methyl-7-(2-oxo-2- phenylethyl)-1H-purine-2,6-dione;

Chemical Property of 8-bromo-3-methyl-7-(2-oxo-2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione

Chemical Property:

• PSA: 89.75000
• LogP: 1.06870

Purity/Quality:

98%min ^*data from raw suppliers

8-Bromo-3-methyl-7-(2-oxo-2-phenylethyl)-1H-purine-2,6(3H,7H)-dione 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-bromo-3-methyl-7-(2-oxo-2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione

There total 1 articles about 8-bromo-3-methyl-7-(2-oxo-2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

potassium salt of 3-methyl-8-bromoxanthine (93703-25-4) + α-bromoacetophenone (70-11-1) → 8-bromo-3-methyl-7-phenacylmethylxanthine (101072-04-2)

Guidance literature:

In N,N-dimethyl-formamide; for 1.5h; Heating;

DOI:10.1007/BF00766906 DOI:10.1007/BF00758812

Reference yield: 97.0%

8-bromo-3-methyl-7-phenacylmethylxanthine (101072-04-2) → 1-Methyl-7-phenyl-1H-oxazolo[2,3-f]purine-2,4-dione (118888-53-2)

Guidance literature:

With sodium benzoate; In N,N-dimethyl-formamide; for 0.833333h;

DOI:10.1007/BF00478866

Reference yield: 79.0%

8-bromo-3-methyl-7-phenacylmethylxanthine (101072-04-2) + 4-hydroxybenzoic acid hydrazide (5351-23-5) → 1-(4-Hydroxy-benzoyl)-8-methyl-3-phenyl-1,4-dihydro-8H-1,2,4a,6,8,9-hexaaza-fluorene-5,7-dione

Guidance literature:

In N,N-dimethyl-formamide; for 1.5h; Heating;

DOI:10.1007/BF00766906

upstream raw materials:

potassium salt of 3-methyl-8-bromoxanthine

α-bromoacetophenone

Downstream raw materials:

1-ethyl-8-methyl-2-phenyl-6H-imidazo<1,2-f>xanthine

3-Methyl-7-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione

1-Methyl-7-phenyl-1H-oxazolo[2,3-f]purine-2,4-dione

(8-methyl-1-ethyl-2-phenylimidazo<1,2-f>xanthin-6-yl)ethanal