Technology Process of p-iodophenyl-p-(1-pyrenyl)phenyldimethylsilane
There total 1 articles about p-iodophenyl-p-(1-pyrenyl)phenyldimethylsilane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-bromopyrene;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
Inert atmosphere;
With
ZnCl2-TMEDA;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
Inert atmosphere;
bis(4-iodophenyl)dimethylsilane;
With
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
for 48.5h;
Inert atmosphere;
DOI:10.1021/ol302742g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate; copper(ll) sulfate pentahydrate / dodecane / 72 h / 220 °C / Inert atmosphere; Schlenk technique
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -100 °C / Inert atmosphere
2.2: 17 h / -100 - 20 °C / Inert atmosphere
With
n-butyllithium; copper(ll) sulfate pentahydrate; potassium carbonate;
In
tetrahydrofuran; dodecane; hexane;
1.1: |Ullmann Condensation;
DOI:10.1021/ol302742g
