Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Base Information

Chemical Name:Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester
CAS No.:121425-43-2
Molecular Formula:C₃₅H₄₉IO₇Si
Molecular Weight:736.76
Hs Code.:

Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Synonyms:

Suppliers and Price of Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

There total 8 articles about Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2R,3R,4R)-3-Acetoxy-2-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-4-methyl-hex-5-enoic acid

: 121425-43-2
Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Guidance literature:: With iodine; sodium hydrogencarbonate; In dichloromethane; Yield given;
DOI:10.1021/jo00274a008

Reference yield:

: 106568-13-2,121440-66-2
(2R,3R,4R)-5-((tert-butyldiphenylsilyl)oxy)-2,4-dimethyl-3-((triethylsilyl)oxy)pentanal

: 121425-43-2
Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) Bu₂BOTf, Et₃N, 2.) H₂O₂ / 1.) CH₂Cl₂, from -78 deg C to -50 deg C, 2.) pH 7

2: pTsOH, H₂O / tetrahydrofuran

3: pTsOH

4: 1.) O₃, 2.) Me₂S / 1.) MeOH, -78 deg C

5: CrCl₂ / tetrahydrofuran / -25 °C

6: pyridine

7: LiOH, H₂O₂ / methanol

8: I₂, NaHCO₃ / CH₂Cl₂

With pyridine; chromium dichloride; lithium hydroxide; dimethylsulfide; di-n-butylboryl trifluoromethanesulfonate; water; dihydrogen peroxide; iodine; sodium hydrogencarbonate; toluene-4-sulfonic acid; ozone; triethylamine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo00274a008

Reference yield:

: 3-[(2S,3R,4R,5R,6R)-7-(tert-Butyl-diphenyl-silanyloxy)-3,5-dihydroxy-4,6-dimethyl-2-vinyl-heptanoyl]-oxazolidin-2-one

: 121425-43-2
Acetic acid (3R,4R,5S,6S)-3-{(4R,5R,6R)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-6-iodomethyl-5-methyl-2-oxo-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 6 steps

1: pTsOH

2: 1.) O₃, 2.) Me₂S / 1.) MeOH, -78 deg C

3: CrCl₂ / tetrahydrofuran / -25 °C

4: pyridine

5: LiOH, H₂O₂ / methanol

6: I₂, NaHCO₃ / CH₂Cl₂

With pyridine; chromium dichloride; lithium hydroxide; dimethylsulfide; dihydrogen peroxide; iodine; sodium hydrogencarbonate; toluene-4-sulfonic acid; ozone; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo00274a008