p-nitrocinnamyl chloride

Base Information

• Chemical Name: p-nitrocinnamyl chloride
• CAS No.: 1507-90-0
• Molecular Formula: C₉H₈ClNO₂
• Molecular Weight: 197.621
• Mol file: 1507-90-0.mol

Synonyms:

Chemical Property of p-nitrocinnamyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-nitrocinnamyl chloride

There total 3 articles about p-nitrocinnamyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

3-(4-nitrophenyl)propyl-2-en-1-ol (35271-56-8,142917-82-6,1504-63-8) → p-nitrocinnamyl chloride (1507-90-0)

Guidance literature:

With dmap; triethylamine; p-toluenesulfonyl chloride; In dichloromethane; at 0 - 15 ℃; for 12.5h;

DOI:10.3390/molecules16075665

Reference yield:

3-(4-nitrophenyl)-2-propenal (1734-79-8) → p-nitrocinnamyl chloride (1507-90-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: aq. HCl

With hydrogenchloride; sodium tetrahydroborate;

DOI:10.1021/jm00327a010

Reference yield:

→ p-nitrocinnamyl chloride (1507-90-0)

Guidance literature:

1percent 4-Nitro-zimtaldehyd enth. 4-Nitrozimtalkohol, Chlf., Thionylchlorid, zuletzt 50-60grad (in geringer Menge neben α-(4-Nitro-phenyl)-allylchlorid);

DOI:10.1016/S0040-4020(01)98442-X

upstream raw materials:

3-(4-nitrophenyl)propyl-2-en-1-ol

3-(4-nitrophenyl)-2-propenal

Downstream raw materials:

bis(μ-chloro)bis(1-(4-nitrophenyl)-η(3)-allyl)dipalladium

Refernces

• 1、 Ding, Rui,He, Yong,Wang, Xiao,Xu, Jingli,Chen, Yurong,Feng, Man,Qi, Chuanmin. "Treatment of alcohols with tosyl chloride does not always lead to the formation of tosylates". experimental part. p. 5665 - 5673. Retrieved 2011/09/20.