methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate

Base Information

• Chemical Name: methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate
• CAS No.: 154749-98-1
• Molecular Formula: C₄₅H₄₂N₆O₅
• Molecular Weight: 746.866
• Mol file: 154749-98-1.mol

Synonyms:

Chemical Property of methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate

There total 2 articles about methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-ethyl-2-n-propyl-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-methyl)imidazole-5-carboxylic acid (139964-19-5) → methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate (154749-98-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 6.46 g / Et₃N / CH₂Cl₂

2: K₂CO₃; KI / dimethylformamide

With potassium carbonate; triethylamine; potassium iodide; In dichloromethane; N,N-dimethyl-formamide; 1: Alkylation / 2: Esterification;

DOI:10.1023/A:1016228129729

Reference yield:

chloromethyl methyl carbonate (40510-81-4) + 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazole-5-yl))biphenyl-4-yl]methyl]-imidazole-5-carboxylate (154749-89-0) → methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate (154749-98-1)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide;

DOI:10.1023/A:1016228129729

Reference yield:

methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazol-5-yl))biphenyl-4-yl]methyl]imidazole-5-carboxylate (154749-98-1) → methoxycarbonyloxymethyl 4-ethyl-2-propyl-1-[[2'-(tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole-5-carboxylate

Guidance literature:

With hydrogenchloride; In methanol;

DOI:10.1023/A:1016228129729

upstream raw materials:

chloromethyl methyl carbonate

4-ethyl-2-propyl-1-[[2'-(N-triphenylmethyl(tetrazole-5-yl))biphenyl-4-yl]methyl]-imidazole-5-carboxylate

4-ethyl-2-n-propyl-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-methyl)imidazole-5-carboxylic acid