4,4'-(Piperazine-1,4-diyl)dibenzaldehyde

Base Information

• Chemical Name: 4,4'-(Piperazine-1,4-diyl)dibenzaldehyde
• CAS No.: 10159-39-4
• Molecular Formula: C18H18N2O2
• Molecular Weight: 294.353
• NSC Number: 725988
• DSSTox Substance ID: DTXSID70388302
• Nikkaji Number: J796.595H
• Wikidata: Q82183174
• Mol file: 10159-39-4.mol

Synonyms:4,4'-(Piperazine-1,4-diyl)dibenzaldehyde;10159-39-4;4-[4-(4-formylphenyl)piperazin-1-yl]benzaldehyde;Benzaldehyde, 4,4'-(1,4-piperazinediyl)bis-;4,4/'-(1,4-piperazinediyl)bis-Benzaldehyde;SCHEMBL3077544;YSZC2201;DTXSID70388302;FZUIYMOPBHBVJH-UHFFFAOYSA-N;4,4-piperazinediyl)bisbenzaldehyde;NSC725988;NSC-725988;4,4'-(1,4-piperazinediyl)dibenzaidehyde;4,4'-(1,4-Piperazinediyl)bisbenzaldehyde;4,4'-(Piperazine-1,4-diyl)bisbenzaldehyde;F86973

Chemical Property of 4,4'-(Piperazine-1,4-diyl)dibenzaldehyde

Chemical Property:

• PSA: 40.62000
• LogP: 2.76820
• Storage Temp.: 2-8°C
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 294.136827821
• Heavy Atom Count: 22
• Complexity: 327

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4'-(PIPERAZINE-1,4-DIYL)DIBENZALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCN1C2=CC=C(C=C2)C=O)C3=CC=C(C=C3)C=O

Technology Process of 4,4'-(Piperazine-1,4-diyl)dibenzaldehyde

There total 2 articles about 4,4'-(Piperazine-1,4-diyl)dibenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

piperazine (110-85-0) + 4-fluorobenzaldehyde (459-57-4) → 4,4’-(1,4-piperazinediyl)bisbenzaldehyde (10159-39-4)

Guidance literature:

In 2-methoxy-ethanol; water; for 12h; Reflux;

Reference yield: 72.0%

1,4-diphenyl-piperazine (613-39-8) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 4,4’-(1,4-piperazinediyl)bisbenzaldehyde (10159-39-4)

Guidance literature:

With trichlorophosphate;

DOI:10.1016/S0968-0896(03)00027-0

Reference yield: 95.0%

4,4’-(1,4-piperazinediyl)bisbenzaldehyde (10159-39-4) → C18H22N2O2 (1258379-36-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 3h;

DOI:10.1039/c0nj00264j

upstream raw materials:

piperazine

4-fluorobenzaldehyde

1,4-diphenyl-piperazine

N,N-dimethyl-formamide

Downstream raw materials:

C₁₈H₂₂N₂O₂

C₂₆H₄₀N₂O₆P₂

Refernces

Preparation, characterization, and proton-induced fluorescence switching of two Ru(II) polypyridyl complexes containing different N-Heterocyclic groups

10.5560/ZNB.2012-0103

The research focuses on the preparation, characterization, and proton-induced fluorescence switching of two Ru(II) polypyridyl complexes that contain different N-heterocyclic groups, specifically imidazole, piperazine, or morpholine units. The purpose of this study was to develop luminescent Ru(II) complexes with a broad pH-sensing range, which can be used as "off-on-off" fluorescence pH sensors. The research concluded that both complexes exhibit strong dependence of their photophysical properties on solution pH and can act as effective pH sensors with a maximum on-off ratio of 6, making them potentially useful for detecting pH changes in environmental settings. In the process, various chemicals were used, including 1,10-phenanthroline-5,6-dione, 4,4’-(1,4-piperazinediyl)bisbenzaldehyde, 4-morpholinobenzaldehyde, Ru(bpy)2Cl2·2H2O, 2,2’-bipyridine, NH4OAc, CH3CN, P2O5, NH4PF6, and other solvents and reagents such as ethylene glycol, RuCl3·3H2O, CH3COOH, CH3CN, EtOH, CH2Cl2, and DMF.