3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate

Base Information

• Chemical Name: 3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate
• CAS No.: 1352127-71-9
• Molecular Formula: C₃₇H₆₀O₂Sn
• Molecular Weight: 655.592
• Mol file: 1352127-71-9.mol

Synonyms:

Chemical Property of 3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate

There total 2 articles about 3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-phenylpropyl 2,4,6-triisopropylbenzoate (1338073-31-6) + tributyltin chloride (1461-22-9) → (S)-3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate (1352127-71-9,1352127-72-0)

Guidance literature:

With sec-butyl lithium; (-)-sparteine; In diethyl ether; ester treated with s-BuLi and (-)-sparteine in Et2O at -78°C; treatment with Bu3SnCl;

DOI:10.1039/c1cc14469c

Reference yield:

3-phenylpropyl 2,4,6-triisopropylbenzoate (1338073-31-6) + tributyltin chloride (1461-22-9) → (S)-3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate (1352127-71-9,1352127-72-0) + 3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate

Guidance literature:

3-phenylpropyl 2,4,6-triisopropylbenzoate; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; sparteine; In diethyl ether; hexane; cyclohexane; at -78 ℃; for 4h; Inert atmosphere;

tributyltin chloride; In diethyl ether; hexane; cyclohexane; at -78 - 20 ℃; for 0.5h; Overall yield = 82percent; Overall yield = 431 g;

DOI:10.1021/acs.orglett.9b03901

Reference yield: 86.0%

(S)-3-phenyl-1-(tributylstannyl)propyl 2,4,6-triisopropylbenzoate (1352127-71-9,1352127-72-0) + 2-(3-iodobut-3-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → (R)-2-(6-iodo-1-phenylhept-6-en-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:

With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201915409

upstream raw materials:

3-phenylpropyl 2,4,6-triisopropylbenzoate

tributyltin chloride

Downstream raw materials:

4,4,5,5-tetramethyl-2-(1-phenylpentan-3-yl)-1,3,2-dioxaborolane