(3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole

Base Information

• Chemical Name: (3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole
• CAS No.: 130132-25-1
• Molecular Formula: C₂₅H₂₈O₆S₂
• Molecular Weight: 488.626
• Mol file: 130132-25-1.mol

Synonyms:

Chemical Property of (3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole

There total 1 articles about (3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-phenyl-1,3-benzodithiolylium trifluoromethanesulfonate + 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (582-52-5) → (3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole (130132-25-1)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0040-4039(00)89023-1

Reference yield: 96.0%

(3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-(2-phenyl-benzo[1,3]dithiol-2-yloxy)-tetrahydro-furo[2,3-d][1,3]dioxole (130132-25-1) → 3-O-benzoyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (13964-22-2)

Guidance literature:

With tetrafluoroboric acid; mercury(II) oxide;

DOI:10.1016/S0040-4039(00)89023-1

upstream raw materials:

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

Downstream raw materials:

3-O-benzoyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose