exo-5-acetylbicyclo<2.2.2>octene

Base Information

• Chemical Name: exo-5-acetylbicyclo<2.2.2>octene
• CAS No.: 40335-83-9
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.221
• Mol file: 40335-83-9.mol

Synonyms:

Chemical Property of exo-5-acetylbicyclo<2.2.2>octene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of exo-5-acetylbicyclo<2.2.2>octene

There total 6 articles about exo-5-acetylbicyclo<2.2.2>octene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl vinyl ketone (78-94-4,25038-87-3) + cyclohexa-1,3-diene (1165952-91-9) → (1R,2R,4R)-1-Bicyclo[2.2.2]oct-5-en-2-yl-ethanone (13398-45-3,13398-62-4,40335-82-8,40335-83-9,40590-77-0,128441-66-7,155156-91-5,185303-22-4)

Guidance literature:

With triethylsilylium tetrakis(pentafluorophenyl), toluene adduct; In toluene; at 0 ℃; for 1h;

DOI:10.1021/ol052206g

Reference yield: 86.0%

methyl vinyl ketone (78-94-4,25038-87-3) + cyclohexa-1,3-diene (1165952-91-9) → (1R,2R,4R)-1-Bicyclo[2.2.2]oct-5-en-2-yl-ethanone (13398-45-3,13398-62-4,40335-82-8,40335-83-9,40590-77-0,128441-66-7,155156-91-5,185303-22-4) + exo-5-acetylbicyclo<2.2.2>octene (13398-45-3,13398-62-4,40335-82-8,40335-83-9,40590-77-0,128441-66-7,155156-91-5,185303-22-4)

Guidance literature:

With iodine; In acetonitrile; at 25 ℃; for 3h; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/cctc.202100342

Reference yield: 86.0%

methyl vinyl ketone (78-94-4,25038-87-3) + cyclohexa-1,3-diene (1165952-91-9) → (1R,2R,4R)-1-Bicyclo[2.2.2]oct-5-en-2-yl-ethanone (13398-45-3,13398-62-4,40335-82-8,40335-83-9,40590-77-0,128441-66-7,155156-91-5,185303-22-4) + exo-5-acetylbicyclo<2.2.2>octene (13398-45-3,13398-62-4,40335-82-8,40335-83-9,40590-77-0,128441-66-7,155156-91-5,185303-22-4)

Guidance literature:

With iodine; In acetonitrile; at 25 ℃; for 3h; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/cctc.202100342

upstream raw materials:

methyl vinyl ketone

cyclohexa-1,3-diene

Downstream raw materials:

bicyclo[2.2.2]octan-2-one