1,4-benzenebis(3-aminopropanoic acid)

Base Information

• Chemical Name: 1,4-benzenebis(3-aminopropanoic acid)
• CAS No.: 87864-91-3
• Molecular Formula: C₁₂H₁₆N₂O₄
• Molecular Weight: 252.27
• Mol file: 87864-91-3.mol

Synonyms:

Chemical Property of 1,4-benzenebis(3-aminopropanoic acid)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-benzenebis(3-aminopropanoic acid)

There total 1 articles about 1,4-benzenebis(3-aminopropanoic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

malonic acid (141-82-2) + terephthalaldehyde, (623-27-8) → 1,4-benzenebis(3-aminopropanoic acid) (87864-91-3)

Guidance literature:

With ammonium acetate; In ethanol; for 20h; Yield given; Heating;

DOI:10.1002/jhet.5570200453

Reference yield:

1,4-benzenebis(3-aminopropanoic acid) (87864-91-3) → diethyl 1,4-benzenebis-3(2,2-diethoxyethylideneamino)propanoate

Guidance literature:

Multi-step reaction with 2 steps

1: 1) SOCl₂ / 2) reflux, 10 min.

2: 1) 10 M NaOH / 1) water, benzene; 2) distillation

With sodium hydroxide; thionyl chloride;

DOI:10.1002/jhet.5570200453

Reference yield:

ethanol (64-17-5) + 1,4-benzenebis(3-aminopropanoic acid) (87864-91-3) → diethyl 1,4-benzenebis(3-aminopropanoate) dihydrochloride (87864-92-4)

Guidance literature:

With thionyl chloride; Yield given. Multistep reaction; 2) reflux, 10 min.;

DOI:10.1002/jhet.5570200453

upstream raw materials:

malonic acid

terephthalaldehyde,

Downstream raw materials:

diethyl 1,4-benzenebis(3-aminopropanoate) dihydrochloride