benzoylamide deferoxamine

Base Information

• Chemical Name: benzoylamide deferoxamine
• CAS No.: 105185-40-8
• Molecular Formula: C₃₂H₅₂N₆O₉
• Molecular Weight: 664.8
• Mol file: 105185-40-8.mol

Synonyms:

Chemical Property of benzoylamide deferoxamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoylamide deferoxamine

There total 13 articles about benzoylamide deferoxamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

deferoxamine (70-51-9) + benzoyl chloride (98-88-4) → benzoylamide deferoxamine (105185-40-8)

Guidance literature:

In chloroform; at 20 ℃; for 0.5h; pH=8 - 9;

DOI:10.1002/1520-6017(200012)89:12<1525::AID-JPS3>3.0.CO;2-T

Reference yield:

N-(5-iodo-pentyl)-benzamide (93432-24-7) → benzoylamide deferoxamine (105185-40-8)

Guidance literature:

Multi-step reaction with 5 steps

1: AgNO₂

2: aq. NH₄Cl, Zn / ethanol

3: Py

4: DCC / tetrahydrofuran / 24 h / Ambient temperature

5: (i) H₂, Pd-C, MeOH, (ii) /BRN= 820616/, THF

With pyridine; silver(I) nitrite; ammonium chloride; dicyclohexyl-carbodiimide; zinc; In tetrahydrofuran; ethanol;

DOI:10.1002/hlca.19620450228

Reference yield:

1-(Carbobenzoxyamino)-5-(hydroxyamino)pentane (91905-05-4) → benzoylamide deferoxamine (105185-40-8)

Guidance literature:

Multi-step reaction with 5 steps

1: Py

2: acetic anhydride / 5 h / 95 - 100 °C

3: (i) NaOMe, MeOH, (ii) /BRN= 898057/, THF

4: (i) aq. NH₄Cl, Zn, EtOH, (ii) /BRN= 385737/, Py

5: (i) H₂, Pd-C, MeOH, (ii) /BRN= 820616/, THF

With pyridine; In acetic anhydride;

DOI:10.1002/hlca.19620450228

upstream raw materials:

N⁽¹⁾-Benzyloxycarbonyl-6,17-dihydroxy-7,10,18-trioxo-6,11,17-triazanonadecylamin

2-(5-benzoylamino-pentyl)-[1,2]oxazinane-3,6-dione

deferoxamine

benzoyl chloride

Downstream raw materials:

C₆H₅C(O)NHC₂₅H₄₃N₅O₈^(3-)*Fe⁽³⁺⁾=C₆H₅C(O)NHC₂₅H₄₃FeN₅O₈

Refernces