As-(p-cyanobenzyl)triphenylarsonium bromide

Base Information

• Chemical Name: As-(p-cyanobenzyl)triphenylarsonium bromide
• CAS No.: 112681-06-8
• Molecular Formula: Br*C₂₆H₂₁AsN
• Molecular Weight: 502.285
• Mol file: 112681-06-8.mol

Synonyms:

Chemical Property of As-(p-cyanobenzyl)triphenylarsonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of As-(p-cyanobenzyl)triphenylarsonium bromide

There total 1 articles about As-(p-cyanobenzyl)triphenylarsonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

triphenyl-arsane (603-32-7) + 4-cyanobenzyl bromide (17201-43-3) → As-(p-cyanobenzyl)triphenylarsonium bromide (112681-06-8)

Guidance literature:

DOI:10.1080/15421400701205784

Reference yield: 79.0%

4-(tetrahydropyran-2-yloxy)benzaldehyde (74189-56-3) + As-(p-cyanobenzyl)triphenylarsonium bromide (112681-06-8) → 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile (136827-57-1)

Guidance literature:

As-(p-cyanobenzyl)triphenylarsonium bromide; With sodium hydride;

4-(tetrahydropyran-2-yloxy)benzaldehyde;

With hydrogenchloride;

DOI:10.1080/15421400701205784

Reference yield:

As-(p-cyanobenzyl)triphenylarsonium bromide (112681-06-8) → 4-{2-[4-(6-oxo-hexyloxy)-phenyl]-vinyl}-benzonitrile (1009342-37-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaH

1.3: 79 percent / HCl

2.1: 70 percent / K₂CO₃

3.1: 82 percent / oxalyl chloride; DMSO / CH₂Cl₂ / 0.67 h / -78 °C

With oxalyl dichloride; sodium hydride; potassium carbonate; dimethyl sulfoxide; In dichloromethane; 3.1: Swern oxidation reaction;

DOI:10.1080/15421400701205784

upstream raw materials:

triphenyl-arsane

4-cyanobenzyl bromide

Downstream raw materials:

4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile

4-{2-[4-(6-oxo-hexyloxy)-phenyl]-vinyl}-benzonitrile

4-{2-[4-(7-oxo-heptyloxy)-phenyl]-vinyl}-benzonitrile

4-{2-[4-(6-hydroxy-hexyloxy)-phenyl]-vinyl}-benzonitrile