cis chloro-3 -2 tetrahydropyranne

Base Information

• Chemical Name: cis chloro-3 -2 tetrahydropyranne
• CAS No.: 118971-83-8
• Molecular Formula: C₁₇H₁₉ClO₇
• Molecular Weight: 370.787
• Mol file: 118971-83-8.mol

Synonyms:

Chemical Property of cis chloro-3 -2 tetrahydropyranne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis chloro-3 -2 tetrahydropyranne

There total 4 articles about cis chloro-3 -2 tetrahydropyranne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) → trans chloro-3 -2 tetrahydropyranne (118971-83-8,118971-84-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 38 percent / pyridine / 5 h / Ambient temperature

2: triphenylphosphine, azodicarboxylate d'isopropyle / toluene / 12 h / Ambient temperature

With pyridine; di-isopropyl azodicarboxylate; triphenylphosphine; In toluene;

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) → cis chloro-3 -2 tetrahydropyranne (118971-83-8,118971-84-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 38 percent / pyridine / 5 h / Ambient temperature

2: triphenylphosphine, azodicarboxylate d'isopropyle / toluene / 12 h / Ambient temperature

With pyridine; di-isopropyl azodicarboxylate; triphenylphosphine; In toluene;

Reference yield:

acetic acid 5-acetoxy-2-acetyl-3-hydroxyphenyl ester (17820-33-6) + trans-3-chloro-2-hydroxytetrahydropyran (1003-57-2,6559-27-9,14750-33-5) → trans chloro-3 -2 tetrahydropyranne (118971-83-8,118971-84-9) + cis chloro-3 -2 tetrahydropyranne (118971-83-8,118971-84-9)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; for 12h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

upstream raw materials:

acetic acid 5-acetoxy-2-acetyl-3-hydroxyphenyl ester

trans-3-chloro-2-hydroxytetrahydropyran

2,4,6-trihydroxyacetophenone