1,2-difluoro-4-dodecylphenylboronic acid

Base Information

• Chemical Name: 1,2-difluoro-4-dodecylphenylboronic acid
• CAS No.: 1385021-17-9
• Molecular Formula: C₁₈H₂₉BF₂O₂
• Molecular Weight: 326.235
• Mol file: 1385021-17-9.mol

Synonyms:

Chemical Property of 1,2-difluoro-4-dodecylphenylboronic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of 1,2-difluoro-4-dodecylphenylboronic acid

There total 1 articles about 1,2-difluoro-4-dodecylphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Trimethyl borate (121-43-7,63156-11-6) + 1,2-difluoro-3-dodecylbenzene (1385021-16-8) → 1,2-difluoro-4-dodecylphenylboronic acid (1385021-17-9)

Guidance literature:

With HCl; Li(CH₂)3CH₃; In tetrahydrofuran; hexane; (under N2); soln. of Li(CH2)3CH3 in hexane added dropwise to THF soln. of ligand at -78°C, stirred for 2 h, cooled B(OCH3)3 added slowly,warmed to room temp., stirred overnight, stirred for 1 h with aq. HCl; extd. with Et2O, organic layer washed with H2O, dried over MgSO4, solvent removed under reduced pressure, recrystd. from hexane;

DOI:10.1039/c2dt30071k

upstream raw materials:

Trimethyl borate

1,2-difluoro-3-dodecylbenzene