4-chloro-2-nitro-N-(2-phenylethyl)aniline

Base Information

• Chemical Name: 4-chloro-2-nitro-N-(2-phenylethyl)aniline
• CAS No.: 100716-41-4
• Molecular Formula: C₁₄H₁₃ClN₂O₂
• Molecular Weight: 276.722
• Mol file: 100716-41-4.mol

Synonyms:

Chemical Property of 4-chloro-2-nitro-N-(2-phenylethyl)aniline

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

(4-Chloro-2-nitrophenyl)(2-phenylethyl)amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-chloro-2-nitro-N-(2-phenylethyl)aniline

There total 3 articles about 4-chloro-2-nitro-N-(2-phenylethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.2%

1-phenyl-2-bromoethane (103-63-9) + 4-Chloro-2-nitroaniline (89-63-4) → 4-chloro-2-nitro-N-phenethylbenzenamine (100716-41-4)

Guidance literature:

With sodium hydroxide; In toluene; at 20 - 70 ℃;

DOI:10.1248/cpb.58.918

Reference yield:

phenethylamine (64-04-0) + 2,5-dichloronitrobenzene (89-61-2) → 4-chloro-2-nitro-N-phenethylbenzenamine (100716-41-4)

Guidance literature:

at 2 ℃; Heating;

DOI:10.1007/s11178-005-0043-z

Reference yield:

→ 4-chloro-2-nitro-N-phenethylbenzenamine (100716-41-4)

Guidance literature:

1) 1.4-Dichlor-2-nitrobenzol, β-Phenylaethylamin, sd. Xylol (6h) 2) Befreiung vom ausgeschiedenen Phenylaethylaminhydrochlorid;

DOI:10.1021/jo01064a613

upstream raw materials:

phenethylamine

2,5-dichloronitrobenzene

1-phenyl-2-bromoethane

4-Chloro-2-nitroaniline

Downstream raw materials:

phenyl N-(4-chloro-2-nitrophenyl)-N-(2-phenylethyl)carbamate