(S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester

Base Information

• Chemical Name: (S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester
• CAS No.: 119255-38-8
• Molecular Formula: C₄₁H₃₆NO₈PS₂
• Molecular Weight: 765.844
• Mol file: 119255-38-8.mol

Synonyms:

Chemical Property of (S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester

There total 1 articles about (S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(S,S')-diphenylphosphorodithioate (23282-01-1) + Nα-(tert-butoxycarbonyl)tyrosine anthraquinon-2-ylmethylester (119255-37-7) → (S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester (119255-38-8)

Guidance literature:

With 2,4,6-triisopropylphenylsulfonyl chloride; In pyridine;

Reference yield:

(S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester (119255-38-8) → C35H33NO12P2S

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorous acid

2: 62 percent / tri-n-butylammonium dihidrogen phosphate / pyridine

With phosphonic Acid; Phosphoric acid tri-n-butylammonium salt; In pyridine;

Reference yield:

(S)-3-[4-(Bis-phenylsulfanyl-phosphoryloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester (119255-38-8) → (S)-2-tert-Butoxycarbonylamino-3-[4-(hydroxy-phenylsulfanyl-phosphoryloxy)-phenyl]-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester (119255-41-3)

Guidance literature:

With phosphonic Acid;

upstream raw materials:

(S,S')-diphenylphosphorodithioate

N^α-(tert-butoxycarbonyl)tyrosine anthraquinon-2-ylmethylester

Downstream raw materials:

O-(S,S-Diphenyl)phosphorodithioyl Boc-tyrosine

(S)-2-tert-Butoxycarbonylamino-3-[4-(hydroxy-phenylsulfanyl-phosphoryloxy)-phenyl]-propionic acid 9,10-dioxo-9,10-dihydro-anthracen-2-ylmethyl ester