Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)]

Base Information

• Chemical Name: Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)]
• CAS No.: 745825-79-0
• Molecular Formula: C₂₄H₁₆F₃O₃Re
• Molecular Weight: 595.591
• Mol file: 745825-79-0.mol

Synonyms:

Chemical Property of Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)]

There total 1 articles about Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 4.1%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + tricarbonylcyclopentadienylrhenium + 2'-((p-α,α,α-trifluorotolyl)ethynyl)acetophenone (745825-76-7) → Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)] (745825-79-0)

Guidance literature:

In tetrahydrofuran; Irradiation (UV/VIS); a THF soln. of CpRe(CO)3 was photolyzed with a Hg-lamp for 30 min at 0°C with continuous N2 purging under IR monitoring, alkyne was added, soln. was concd., stirred under N2 at 0°C for 2 h and at room temp. for addnl. 3 h; preparative TLC (silica gel, 2:1 pentane/ether);

DOI:10.1021/om040063g

Reference yield: 81.0%

Cp(CO)2Re=C(p-α,α,α-trifluorotolyl)(3-methylisobenzofur-1-yl) + Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)] (745825-79-0) + dimethyl acetylenedicarboxylate (762-42-5) → Cp(CO)2Re=C(C6H4-p-CF3)(C15H13O5)

Guidance literature:

In dichloromethane-d2; DMAD was added to an equil. mixt. of alkyne-carbene complexes in CD2Cl2,the mixt. was heated for 44 h at 38°C; reaction was monitored by NMR spectroscopy; evapd. under vac., residue wsa crystd. from CH2Cl2-pentane;

DOI:10.1021/om040063g

Reference yield:

Cp(CO)2Re[η2-(2'-(p-(α,α,α-trifluoropolyl)ethynyl)acetophenone)] (745825-79-0) → Cp(CO)2Re=C(p-α,α,α-trifluorotolyl)(3-methylisobenzofur-1-yl)

Guidance literature:

In benzene-d6; a soln. of Re-alkyne complex was degassed by 3 freze-pump-thaw cycles, heated at 38°C for 3 d, the reaction being monitored by NMR spectroscopy; reversible reaction, 38:62 equil. mixt. of alkyne-carbene complexes was formed, K(equil.)=1.63; not isolated; detd. by (1)H and (13)C NMR spectral data;

DOI:10.1021/om040063g

upstream raw materials:

tetrahydrofuran

2'-((p-α,α,α-trifluorotolyl)ethynyl)acetophenone

Downstream raw materials:

Cp(CO)2Re[η2-O=C(p-CF3C6H4)(2-C(17)OC6H4COMe)]

Cp(CO)2Re[η2-O=C(p-CF3C6H4)(2-COC6H4C(17)OMe)]

Cp(CO)2Re[η2-O=C(p-CF3C6H4)(2-COC6H4Ac)]