Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)-

Base Information

Chemical Name:Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)-
CAS No.:85148-84-1
Molecular Formula:C₁₂H₂₀O₃
Molecular Weight:212.289
Hs Code.:
DSSTox Substance ID:DTXSID001165114

Synonyms:DTXSID001165114;Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)-;85148-84-1

Suppliers and Price of Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:212.14124450
Heavy Atom Count:15
Complexity:291

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC=C1CCCC(C1(CC(=O)O)O)(C)C
Isomeric SMILES:C/C=C/1\CCCC(C1(CC(=O)O)O)(C)C

Technology Process of Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)-

There total 3 articles about Cyclohexaneacetic acid, 6-ethylidene-1-hydroxy-2,2-dimethyl-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1193-47-1
2,2-dimethyl-cyclohexanone

: 85148-84-1
[6-Eth-(E)-ylidene-1-hydroxy-2,2-dimethyl-cyclohexyl]-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BuLi, diisopropylamine / 1.) hexane, THF, -78 deg C, 30 min, 2.) THF, 45 min

2: p-toluenesulfonic acid / benzene / 1.5 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; diisopropylamine; In benzene;
DOI:10.1055/s-1982-30093

Reference yield:

: 344296-65-7
6-(1-Hydroxy-ethyl)-2,2-dimethyl-cyclohexanone

: 85148-84-1
[6-Eth-(E)-ylidene-1-hydroxy-2,2-dimethyl-cyclohexyl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: p-toluenesulfonic acid / benzene / 1.5 h / Heating

With toluene-4-sulfonic acid; In benzene;
DOI:10.1055/s-1982-30093