(2S,3R)-2-Acetoxy-3-acetylamino-4-cyclohexyl-butyric acid isopropyl ester

Base Information

Chemical Name:(2S,3R)-2-Acetoxy-3-acetylamino-4-cyclohexyl-butyric acid isopropyl ester
CAS No.:141280-91-3
Molecular Formula:C₁₇H₂₉NO₅
Molecular Weight:327.421
Hs Code.:

Synonyms:

Suppliers and Price of (2S,3R)-2-Acetoxy-3-acetylamino-4-cyclohexyl-butyric acid isopropyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-Acetoxy-3-acetylamino-4-cyclohexyl-butyric acid isopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-Acetoxy-3-acetylamino-4-cyclohexyl-butyric acid isopropyl ester

There total 26 articles about (2S,3R)-2-Acetoxy-3-acetylamino-4-cyclohexyl-butyric acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20698-91-3
(R)-methyl mandelate

: 141280-91-3
isopropyl (2R,3S)-3-acetamido-2-acetoxy-4-cyclohexylbutyrate

Guidance literature:: Multi-step reaction with 9 steps

1: 98 percent / imidazole / dimethylformamide / Ambient temperature

2: 82 percent / DIBAL / hexane; diethyl ether / 0.33 h / -78 °C

3: MgSO₄ / toluene / 1 h / 0 °C

4: Et₃N / CH₂Cl₂ / Ambient temperature

5: 84 percent / HCl gas / 1) rt, overnight, 2) 60 deg C, 3 h

6: 90 percent / pyridine / CH₂Cl₂ / 0.17 h / 0 °C

7: 94 percent / H₂ / 10percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature

8: 97 percent / H₂ / 5percent Rh/Al₂O₃ / acetic acid / 3800 Torr / Ambient temperature

9: pyridine / Ambient temperature

With pyridine; 1H-imidazole; hydrogenchloride; hydrogen; diisobutylaluminium hydride; magnesium sulfate; triethylamine; palladium on activated charcoal; Rh/Al₂O₃; In diethyl ether; hexane; dichloromethane; acetic acid; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4020(01)88510-0

Reference yield:

: 130115-07-0
(R)-2-(t-butyldimethylsilyloxy)-2-phenylacetaldehyde

: 141280-91-3
isopropyl (2R,3S)-3-acetamido-2-acetoxy-4-cyclohexylbutyrate

Guidance literature:: Multi-step reaction with 7 steps

1: MgSO₄ / toluene / 1 h / 0 °C

2: Et₃N / CH₂Cl₂ / Ambient temperature

3: 84 percent / HCl gas / 1) rt, overnight, 2) 60 deg C, 3 h

4: 90 percent / pyridine / CH₂Cl₂ / 0.17 h / 0 °C

5: 94 percent / H₂ / 10percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature

6: 97 percent / H₂ / 5percent Rh/Al₂O₃ / acetic acid / 3800 Torr / Ambient temperature

7: pyridine / Ambient temperature

With pyridine; hydrogenchloride; hydrogen; magnesium sulfate; triethylamine; palladium on activated charcoal; Rh/Al₂O₃; In dichloromethane; acetic acid; ethyl acetate; toluene;
DOI:10.1016/S0040-4020(01)88510-0

Reference yield:

: 124876-74-0
Methyl (R)-(-)-α-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-α-phenylacetate

: 141280-91-3
isopropyl (2R,3S)-3-acetamido-2-acetoxy-4-cyclohexylbutyrate

Guidance literature:: Multi-step reaction with 8 steps

1: 82 percent / DIBAL / hexane; diethyl ether / 0.33 h / -78 °C

2: MgSO₄ / toluene / 1 h / 0 °C

3: Et₃N / CH₂Cl₂ / Ambient temperature

4: 84 percent / HCl gas / 1) rt, overnight, 2) 60 deg C, 3 h

5: 90 percent / pyridine / CH₂Cl₂ / 0.17 h / 0 °C

6: 94 percent / H₂ / 10percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature

7: 97 percent / H₂ / 5percent Rh/Al₂O₃ / acetic acid / 3800 Torr / Ambient temperature

8: pyridine / Ambient temperature

With pyridine; hydrogenchloride; hydrogen; diisobutylaluminium hydride; magnesium sulfate; triethylamine; palladium on activated charcoal; Rh/Al₂O₃; In diethyl ether; hexane; dichloromethane; acetic acid; ethyl acetate; toluene;
DOI:10.1016/S0040-4020(01)88510-0