1H-Indole, 4-fluoro-1-(phenylsulfonyl)-

Base Information

Chemical Name:1H-Indole, 4-fluoro-1-(phenylsulfonyl)-
CAS No.:102855-23-2
Molecular Formula:C14H10FNO2S
Molecular Weight:275.303
Hs Code.:
DSSTox Substance ID:DTXSID50545815
Wikidata:Q82423434
Mol file:102855-23-2.mol

Synonyms:102855-23-2;4-Fluoro-1-(phenylsulfonyl)-1H-indole;1-(benzenesulfonyl)-4-fluoroindole;1H-Indole, 4-fluoro-1-(phenylsulfonyl)-;1-(Benzenesulfonyl)-4-fluoro-1H-indole;4-Fluoro-1-benzosulfonyl-1H-indole;SCHEMBL20843619;DTXSID50545815;C91483

Suppliers and Price of 1H-Indole, 4-fluoro-1-(phenylsulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1H-Indole, 4-fluoro-1-(phenylsulfonyl)-

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:275.04162790
Heavy Atom Count:19
Complexity:414

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)N2C=CC3=C2C=CC=C3F

Technology Process of 1H-Indole, 4-fluoro-1-(phenylsulfonyl)-

There total 1 articles about 1H-Indole, 4-fluoro-1-(phenylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 387-43-9
4-fluoroindole

: 98-09-9
benzenesulfonyl chloride

: 102855-23-2
4-fluoro-1-(phenylsulfonyl)-1H-indole

Guidance literature:: 4-fluoroindole; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h;

benzenesulfonyl chloride; In tetrahydrofuran; for 1h;
DOI:10.1021/jm058033i

Reference yield: 88.31%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 102855-23-2
4-fluoro-1-(phenylsulfonyl)-1H-indole

: 4-fluoro-1-(phenylsulfonyl)-1H-indole-2-carbaldehyde

Guidance literature:: 4-fluoro-1-(phenylsulfonyl)-1H-indole; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

N,N-dimethyl-formamide; In tetrahydrofuran; at -78 ℃; for 0.166667h; Inert atmosphere;

Reference yield: 36.0%

: 102855-23-2
4-fluoro-1-(phenylsulfonyl)-1H-indole

: 896137-76-1
5-methoxy-1-phenylsulfonyl-1H-indole-2-carbonyl chloride

: 896137-87-4
(4-fluoro-1-phenylsulfonyl-1H-indol-2-yl)-(5-methoxy-1-phenylsulfonyl-1H-indol-2-yl)methanone

Guidance literature:: 4-fluoro-1-(phenylsulfonyl)-1H-indole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

5-methoxy-1-phenylsulfonyl-1H-indole-2-carbonyl chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃;
DOI:10.1021/jm058033i