threo-1-bromo-2-chloro-1-phenylpropane

Base Information

• Chemical Name: threo-1-bromo-2-chloro-1-phenylpropane
• CAS No.: 94274-77-8
• Molecular Formula: C₉H₁₀BrCl
• Molecular Weight: 233.535
• Mol file: 94274-77-8.mol

Synonyms:

Chemical Property of threo-1-bromo-2-chloro-1-phenylpropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of threo-1-bromo-2-chloro-1-phenylpropane

There total 3 articles about threo-1-bromo-2-chloro-1-phenylpropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-1-phenyl-1-propylene (766-90-5) → threo-1-bromo-2-chloro-1-phenylpropane (94274-77-8,96300-91-3,131340-55-1) + threo-2-bromo-1-chloro-1-phenylpropane (4962-44-1,66323-24-8,91085-88-0)

Guidance literature:

With tetrabutylammonium dichlorobromate; In chloroform; at 0 ℃; for 0.166667h; Yield given. Yields of byproduct given;

DOI:10.1246/bcsj.57.2116

Reference yield:

cis-1-phenyl-1-propylene (766-90-5) → (1-bromoethyl)benzyl bromide (1196-45-8) + threo-1-bromo-2-chloro-1-phenylpropane (94274-77-8,96300-91-3,131340-55-1) + threo-2-bromo-1-chloro-1-phenylpropane (4962-44-1,66323-24-8,91085-88-0)

Guidance literature:

With poly (R = n-C6H13); In dichloromethane; at 23 ℃; for 0.75h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4020(01)87938-2

Reference yield:

cis-1-phenyl-1-propylene (766-90-5) → (Z)-(1-Chloro-1-propenyl)benzene (4541-85-9) + threo-1-bromo-2-chloro-1-phenylpropane (94274-77-8,96300-91-3,131340-55-1)

Guidance literature:

With potassium tert-butylate; tetrabutylammonium dichlorobromate; Yield given. Multistep reaction. Yields of byproduct given; 1.) chloroform, 0 deg C, 10 min, 2.) t-butyl alcohol, 20 deg C, 1 h;

DOI:10.1246/bcsj.57.2116

upstream raw materials:

cis-1-phenyl-1-propylene

Downstream raw materials:

cis-1-bromo-2-methyl-1-phenylethene

Refernces

• 1、 Negoro,Ikeda. "BROMOCHLORINATION OF ALKENES WITH DICHLOROBROMATE(1 minus ) ION. II. REGIO- AND STEREOCHEMISTRY FOR THE BROMOCHLORINATION OF 1-PHENYLPROPENES WITH DICHLOROBROMATE(1 minus ) ION.". . p. 2116 - 2120. Retrieved 2007/10/02.