2-Cyclopenten-1-one, 4-hydroxy-3-methyl-

Base Information

Chemical Name:2-Cyclopenten-1-one, 4-hydroxy-3-methyl-
CAS No.:10288-24-1
Molecular Formula:C6H8O2
Molecular Weight:112.128
Hs Code.:
DSSTox Substance ID:DTXSID30444913

Synonyms:10288-24-1;2-cyclopenten-1-one, 4-hydroxy-3-methyl-;SCHEMBL10385805;DTXSID30444913;4-hydroxy-3-methyl-2-cyclopenten-1-one

Suppliers and Price of 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-

Chemical Property:

XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:112.052429494
Heavy Atom Count:8
Complexity:147

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=O)CC1O

Technology Process of 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-

There total 1 articles about 2-Cyclopenten-1-one, 4-hydroxy-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17559-81-8
(Z)-hex-3-ene-2,5-dione

: 10288-24-1
3-methyl-4-hydroxy-2-cyclopentenone

Guidance literature:: With sodium carbonate; In water; for 3h; Heating;
DOI:10.1021/ol063052n

Reference yield:

: 10288-24-1
3-methyl-4-hydroxy-2-cyclopentenone

: 935684-22-3
(1R,4R)-4-(tert-butyldimethylsilanyloxy)-2-iodo-3-methylcyclopent-2-enyl 2,3,4,5,6-pentafluorobenzoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: porcine pancreatic lipase; vinyl acetate / 25 °C

1.2: guanidine / methanol / 0.08 h

2.1: imidazole / dimethylformamide / 12 h / 25 °C

3.1: I₂; PDC / CH₂Cl₂ / 48 h / 25 °C

4.1: BH₃*PhNEt₂ / diphenyl((S)-pyrrolidin-2-yl)methanol; B(OMe)3 / tetrahydrofuran / 1.5 h / 25 °C

5.1: 91 percent / DMAP; pyridine / diethyl ether / 2 h / 25 °C

With pyridine; 1H-imidazole; dmap; dipyridinium dichromate; borane N,N-diethylaniline complex; vinyl acetate; porcine pancreatic lipase; iodine; Trimethyl borate; (S)-diphenylprolinol; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol063052n

Reference yield:

: 10288-24-1
3-methyl-4-hydroxy-2-cyclopentenone

: (1R,4S)-4-(tert-butyldimethylsilanyloxy)-2-iodo-3-methylcyclopent-2-enyl 2,3,4,5,6-pentafluorobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 3.39 g / imidazole / dimethylformamide / 12 h / 25 °C

2.1: 77 percent / I₂; PDC / CH₂Cl₂ / 46 h / 25 °C

3.1: BH₃*PhNEt₂ / diphenyl((S)-pyrrolidin-2-yl)methanol; B(OMe)3 / tetrahydrofuran / 1.5 h / 25 °C

3.2: DMAP; pyridine / diethyl ether / 2 h / 25 °C

With 1H-imidazole; dipyridinium dichromate; borane N,N-diethylaniline complex; iodine; Trimethyl borate; (S)-diphenylprolinol; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol063052n