C₁₄H₁₈LiNOSi

Base Information

• Chemical Name: C₁₄H₁₈LiNOSi
• CAS No.: 100573-11-3
• Molecular Formula: C₁₄H₁₈LiNOSi
• Molecular Weight: 251.33
• Mol file: 100573-11-3.mol

Synonyms:

Chemical Property of C₁₄H₁₈LiNOSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₈LiNOSi

There total 2 articles about C₁₄H₁₈LiNOSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-Methyl-4-phenyl-2-trimethylsilanyloxy-but-3-enenitrile (81040-24-6) → C14H18LiNOSi (100573-11-3)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 2h;

Reference yield:

α-methyl-trans-cinnamaldehyde (15174-47-7) → C14H18LiNOSi (100573-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / Bu₄NI / 4 h / 25 °C

2: LiN(iPr)2 / tetrahydrofuran; hexane / 2 h / -78 °C

With tetra-(n-butyl)ammonium iodide; lithium diisopropyl amide; In tetrahydrofuran; hexane;

Reference yield: 66.0%

C14H18LiNOSi (100573-11-3) + methyl iodide (74-88-4) → 2,3-Dimethyl-4-phenyl-2-(trimethylsiloxy)-3-butennitril (100573-18-0)

Guidance literature:

In tetrahydrofuran; hexane; at -78 ℃;

upstream raw materials:

(E)-3-Methyl-4-phenyl-2-trimethylsilanyloxy-but-3-enenitrile

α-methyl-trans-cinnamaldehyde

Downstream raw materials:

2,3-Dimethyl-4-phenyl-2-(trimethylsiloxy)-3-butennitril