Silane, [3-(4-methoxyphenyl)-1-propynyl]trimethyl-

Base Information

• Chemical Name: Silane, [3-(4-methoxyphenyl)-1-propynyl]trimethyl-
• CAS No.: 102987-40-6
• Molecular Formula: C13H18OSi
• Molecular Weight: 218.371
• DSSTox Substance ID: DTXSID90457266
• Nikkaji Number: J1.691.214J
• Wikidata: Q82280049
• Mol file: 102987-40-6.mol

Synonyms:Silane, [3-(4-methoxyphenyl)-1-propynyl]trimethyl-;102987-40-6;DTXSID90457266;4-[3-(Trimethylsilyl)propargyl]anisole

Chemical Property of Silane, [3-(4-methoxyphenyl)-1-propynyl]trimethyl-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 218.112691728
• Heavy Atom Count: 15
• Complexity: 245

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CC#C[Si](C)(C)C

Technology Process of Silane, [3-(4-methoxyphenyl)-1-propynyl]trimethyl-

There total 6 articles about Silane, [3-(4-methoxyphenyl)-1-propynyl]trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-(4-methoxyphenyl)-3-(trimethylsilyl)prop-2-yn-1-ol (159351-36-7) → (3-(4-methoxyphenyl)prop-1-ynyl)trimethylsilane (102987-40-6)

Guidance literature:

With triethylsilane; [(η⁵-C5Me5)RuCl(μ₂-SMe)2Ru(η⁵-C5Me5)(OH2)]OTf; In 1,2-dichloro-ethane; at 80 ℃; for 1h;

DOI:10.1002/anie.200601181

Reference yield: 98.0%

(trimethylsilyl)ethynylmagnesium bromide (61210-52-4) + p-methoxybenzyl chloride (824-94-2) → (3-(4-methoxyphenyl)prop-1-ynyl)trimethylsilane (102987-40-6)

Guidance literature:

With cobalt(III) acetylacetonate; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tetlet.2006.02.028

Reference yield: 94.0%

C14H18O3Si → (3-(4-methoxyphenyl)prop-1-ynyl)trimethylsilane (102987-40-6)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos; In toluene; at 110 ℃; for 15h; Schlenk technique; Inert atmosphere;

DOI:10.1055/s-0037-1609575

upstream raw materials:

1,3-bis(trimethylsilyl)propyne

4-methoxy(diacetoxyiodo)benzene

(trimethylsilyl)ethynylmagnesium bromide

p-methoxybenzyl chloride

Downstream raw materials:

3-(4-methoxyphenyl)prop-1-yne

1‐(4‐methoxyphenyl)‐3‐(trimethylsilyl)prop‐2‐yn‐1‐one

methyl (2E,4E)-6-(4-methoxyphenyl)-2,4-hexadienoate

6-(p-Methoxyphenyl)-hexa-trans-2-trans-4-diensaeure