159351-36-7

Basic information

• Product Name: Benzenemethanol, 4-methoxy-a-[(trimethylsilyl)ethynyl]-
• CAS NO: 159351-36-7
• Molecular Formula: C13H18O2Si
• Molecular Weight: 234.37
• Mol File: 159351-36-7.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-methoxy-a-[(trimethylsilyl)ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-methoxy-a-[(trimethylsilyl)ethynyl]-(159351-36-7)
• EPA Substance Registry System: Benzenemethanol, 4-methoxy-a-[(trimethylsilyl)ethynyl]-(159351-36-7)

Safety Data

• Hazardous Substances Data: 159351-36-7(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 54655-07-1 lithium trimethylsilylacetylenide 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 102987-40-6 (3-(4-methoxyphenyl)prop-1-ynyl)trimethylsilane 
• 1032650-13-7 (3-isopropoxy-3-(4-methoxyphenyl)prop-1-ynyl)trimethylsilane 
• 1252883-20-7 (3-(4-methoxyphenyl)-5-phenylpenta-1,4-diynyl)trimethylsilane 
• 1292806-84-8 (3-(4-methoxyphenyl)-5-(5-methylfuran-2-yl)penta-1,4-diynyl)trimethylsilane 
• 1352742-24-5 (R)-1-(4-methoxyphenyl)-3-(trimethylsilyl)prop-2-ynyl acetate 
• 1614262-05-3 3-(2-((2-chloro-5-(trifluoromethyl)phenyl)ethynyl)phenyl)-1-(4-methoxyphenyl)prop-2-yn-1-one 
• 1614262-02-0 1-(4-methoxyphenyl)-3-(2-((2,3,4,5-tetrafluoro-6-iodophenyl)-ethynyl)phenyl)prop-2-yn-1-one 
• 1614261-98-1 3-(2-((2-bromo-5-(trifluoromethyl)phenyl)ethynyl)phenyl)-1-(4-methoxyphenyl)prop-2-yn-1-one 
• 1614261-94-7 3-(2-((2-bromo-3,4,5,6-tetrafluorophenyl)ethynyl)phenyl)-1-(4-methoxyphenyl)prop-2-yn-1-one 
• 1614261-84-5 3-(2-ethynylphenyl)-1-(4-methoxyphenyl)prop-2-yn-1-ol 
• 1614261-82-3 C₂₁H₂₂O₂Si 
• 1609661-88-2 3-(2-bromophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-ol 
• 1614262-03-1 C₂₅H₁₆ClF₃O₂ 

Relevant articles and documents

Rh(I)-catalyzed cyclization of 1-arylprop-2-yn-1-ol derivatives utilizing rhodium 1,4-migration

A highly useful method for the construction of cyclopentanone derivatives fused with aromatic ring based on hydrorhodation-1,4-rhodium migration sequence is achieved. Treatment of 1-aryl-prop-2-yn-1-ols, which are easily accessible via an addition of acetylides to the corresponding aryl aldehydes, with a catalytic amount of [Rh(cod)2]2(BF4) and P(p-tolyl)3 in the presence of a base gives cyclopentanone derivatives in moderate to good yield. Copyright

Gold-Catalyzed Iminations of Terminal Propargyl Alcohols with Anthranils with Atypical Chemoselectivity for C(1)-Additions and 1,2-Carbon Migration

This work reports gold-catalyzed iminations of terminal propargyl alcohols with anthranils or isoxazoles to yield E-configured α-amino-2-en-1-ones and -1-als with complete chemoselectivity. These catalytic iminations occur exclusively with C(1)-nucleophilic additions on terminal alkynes, in contrast to a typical C(2)-route. For 3,3-dialkylprop-1-yn-3-ols, a methyl substituent is superior to long alkyl chains as the 1,2-migration groups toward α-imino gold carbenes. For secondary prop-1-yn-3-ols, phenyl, vinyl, and cyclopropyl substituents are better than hydrogen as the migrating groups, obviating typical gold carbene reactions. DFT calculations have been performed to rationalize the observed C(1)-regioselectivity and the preferable cyclopropyl migration based on gold carbene pathways.

Iron (III)-Promoted Synthesis of Substituted 4H-Chalcogenochromenes and Chemoselective Functionalization

The iron(III)-promoted synthesis of densely-substituted 4H-chalcogenchromene from organochalcogen propargylamines in the presence of diaryl dichalcogenides is reported. Subsequent C2-functionalization with electrophiles and potassium trifluoroborate salts