N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE

Base Information

• Chemical Name: N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE
• CAS No.: 360-92-9
• Molecular Formula: C6H10F3NO
• Molecular Weight: 169.147
• Hs Code.: 2924199090
• Mol file: 360-92-9.mol

Synonyms:N,N-Diethyl-2,2,2-trifluoroacetamide;N,N-Diethyltrifluoroacetamide;NSC 14815;Trifluoroacetyl diethylamine;N,N-Diethyl-2,2,2-trifluoroacetamide 99%;Diethyltrifluoroacetamide;

Chemical Property of N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE

Chemical Property:

• Vapor Pressure: 0.83mmHg at 25°C
• Refractive Index: n20/D 1.38(lit.)
• Boiling Point: 182 oC
• Flash Point: 63.9 oC
• PSA: 20.31000
• Density: 1.14 g/cm³
• LogP: 1.41710

Purity/Quality:

99.9% ^*data from raw suppliers

N,N-Diethyl-2,2,2-trifluoroacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi,F
• Hazard Codes: Xn,Xi,F
• Statements: 10-20/21/22-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: N,N-Diethyl-2,2,2-trifluoroacetamide can be prepared to use as an important intermediate for pesticides and veterinary drugs.

Technology Process of N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE

There total 3 articles about N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-methylphenyl trifluoroacetate (1813-29-2) + Ethyl-phenyl-phosphingsaere-diethylamid (70795-79-8,71162-24-8,71162-25-9) → N,N-diethyl-2,2,2-trifluoroacetamide (360-92-9) + S(-)-Ethyl-phenyl-phosphinigsaere-p-kresylester

Guidance literature:

for 0.333333h; Ambient temperature;

Reference yield: 80.0%

trifluoroacetic anhydride (407-25-0) + (diethylamino)diphenylphosphine (1636-15-3) → N,N-diethyl-2,2,2-trifluoroacetamide (360-92-9) + Diphenyl-phosphinigsaere-anhydrid

Guidance literature:

In benzene; ice cooling;

Reference yield:

2,2,2-trifluoroethyl trifluoroacetate (407-38-5) + Ethyl-phenyl-phosphingsaere-diethylamid (70795-79-8,71162-24-8,71162-25-9) → N,N-diethyl-2,2,2-trifluoroacetamide (360-92-9) + Ethyl-phenyl-phosphinigsaere-β,β,β-trifluorethylester

Guidance literature:

upstream raw materials:

2,2,2-trifluoroethyl trifluoroacetate

Ethyl-phenyl-phosphingsaere-diethylamid

4-methylphenyl trifluoroacetate

trifluoroacetic anhydride

Downstream raw materials:

2,2,2-trifluoro-1-(3-dimethylaminophenyl)ethanone

N_.N-Dimethylanilyl-2-trifluormethylketon-gem-diol

1-(4-(dimethylamino)phenyl)-2,2,2-trifluoroethanone

tert-butyl 1-(4-(2,2,2-trifluoroacetyl)phenyl)ethylcarbamate

Refernces