Trifluoroacetic acid p-tolyl ester

Base Information

• Chemical Name: Trifluoroacetic acid p-tolyl ester
• CAS No.: 1813-29-2
• Molecular Formula: C9H7F3O2
• Molecular Weight: 204.149
• Hs Code.: 2915900090
• Mol file: 1813-29-2.mol

Synonyms:p-Tolyl trifluoroacetate;Acetic acid, trifluoro-, 4-methylphenyl ester;4-methylphenyl trifluoroacetate;Trifluor-essigsaeure-p-tolylester;Acetic acid,trifluoro-,p-tolyl ester;Acetic acid,trifluoro-,4-methylphenyl ester;trifluoro-acetic acid p-tolyl ester;

Chemical Property of Trifluoroacetic acid p-tolyl ester

Chemical Property:

• Vapor Pressure: 1.94mmHg at 25°C
• Boiling Point: 164.7°C at 760 mmHg
• Flash Point: 33.6°C
• PSA: 26.30000
• Density: 1.278g/cm³
• LogP: 2.46270

Purity/Quality:

99% ^*data from raw suppliers

4-Methylphenyltrifluoroacetate 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Trifluoroacetic acid p-tolyl ester

There total 11 articles about Trifluoroacetic acid p-tolyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

p-cresol (106-44-5) + trifluoroacetic anhydride (407-25-0) → 4-methylphenyl trifluoroacetate (1813-29-2)

Guidance literature:

erbium(III) triflate; In acetonitrile; at 20 ℃; for 8h;

DOI:10.1002/adsc.200404132

Reference yield: 23.0%

toluene (108-88-3,15644-74-3,16713-13-6) + trifluoroacetic acid (76-05-1) → para-chlorotoluene (106-43-4) + 4-methylphenyl trifluoroacetate (1813-29-2) + 2-(trifluoroacetoxy)toluene (1736-10-3)

Guidance literature:

With lead(IV) acetate; lithium chloride; at 25 ℃; for 1h; Mechanism;

Reference yield:

C28H7F39O6Pb (102644-90-6) → para-chlorotoluene (106-43-4) + 4-methylphenyl trifluoroacetate (1813-29-2) + 2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid p-tolyl ester (102607-12-5)

Guidance literature:

With trifluoroacetic acid; lithium chloride;

upstream raw materials:

p-cresol

trifluoroacetic anhydride

C₂₈H₇F₃₉O₆Pb

perfluoroheptanoic acid

Downstream raw materials:

2,2,2-trifluoromethyl-1-(2-hydroxy-5-methylphenyl)ethan-1-one

R(+)-Methyl-phenyl-phospphinigsaere-p-kresylester

N,N-diethyl-2,2,2-trifluoroacetamide

4-methylbenzotrifluoride