1-Hydroxy-7-methoxymitosene chloroacetate

Base Information

• Chemical Name: 1-Hydroxy-7-methoxymitosene chloroacetate
• CAS No.: 78776-10-0
• Molecular Formula: C₁₇H₁₇ClN₂O₇
• Molecular Weight: 396.784
• Mol file: 78776-10-0.mol

Synonyms:

Chemical Property of 1-Hydroxy-7-methoxymitosene chloroacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Hydroxy-7-methoxymitosene chloroacetate

There total 2 articles about 1-Hydroxy-7-methoxymitosene chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.9%

1-hydroxy-7-methoxymitosene (40863-79-4) + chloroacetyl chloride (79-04-9) → 1-Hydroxy-7-methoxymitosene chloroacetate (78776-10-0)

Guidance literature:

With potassium carbonate; In ethyl acetate; for 12h; Ambient temperature;

DOI:10.1021/jm00142a013

Reference yield:

1-Acetoxy-7-methoxymitosene (40863-78-3) → 1-Hydroxy-7-methoxymitosene chloroacetate (78776-10-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 77.7 percent / 30percent ammonium hydroxide / methanol / 10 h / Ambient temperature

2: 48.9 percent / potassium carbonate / ethyl acetate / 12 h / Ambient temperature

With ammonium hydroxide; potassium carbonate; In methanol; ethyl acetate;

DOI:10.1021/jm00142a013

upstream raw materials:

1-hydroxy-7-methoxymitosene

chloroacetyl chloride

1-Acetoxy-7-methoxymitosene