3-Chloro-2-methylpropan-1-ol

Base Information

• Chemical Name: 3-Chloro-2-methylpropan-1-ol
• CAS No.: 10317-10-9
• Molecular Formula: C4H9ClO
• Molecular Weight: 108.56700
• DSSTox Substance ID: DTXSID50445907
• Nikkaji Number: J260.341A
• Mol file: 10317-10-9.mol

Synonyms:3-chloro-2-methylpropan-1-ol;10317-10-9;3-chloro-2-methyl-1-propanol;1-Propanol, 3-chloro-2-methyl-;3-chloro-2-methyl-propan-1-ol;SCHEMBL95986;DTXSID50445907;AKOS006384019

Chemical Property of 3-Chloro-2-methylpropan-1-ol

Chemical Property:

• Refractive Index: 1.4460
• Boiling Point: 122.94°C (rough estimate)
• PSA: 20.23000
• Density: 1.0830
• LogP: 0.85360
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 108.0341926
• Heavy Atom Count: 6
• Complexity: 30.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Chloro-2-methylpropan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CO)CCl
• Uses: 3-Chloro-2-methylpropan-1-ol acts as a reagent use in the oxidation of organoboranes with sodium percarbonate

Technology Process of 3-Chloro-2-methylpropan-1-ol

There total 9 articles about 3-Chloro-2-methylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H19ClOSi → 3-chloro-2-methylpropan-1-ol (10317-10-9)

Guidance literature:

With methanol; water; sodium hydroxide; In acetonitrile; at 20 ℃; for 8h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.1c03029

Reference yield:

trichloro-acetic acid-(γ-chloro-isobutyl ester) → 3-chloro-2-methylpropan-1-ol (10317-10-9)

Guidance literature:

With sodium hydroxide; durch Verseifung;

Reference yield:

1-acetoxy-3-chloro-2-methyl-propane (2159-71-9,82560-89-2) → 3-chloro-2-methylpropan-1-ol (10317-10-9)

Guidance literature:

With hydrogenchloride; In methanol;

upstream raw materials:

1,3-dichloro-2-methylpropane

1-acetoxy-3-chloro-2-methyl-propane

3-Chloro-2-methylpropene

2-methylpropenal