4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide

Base Information

Chemical Name:4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide
CAS No.:41805-00-9
Molecular Formula:C₁₆H₂₃ClN₂O
Molecular Weight:294.824
Hs Code.:
DSSTox Substance ID:DTXSID301342408

Synonyms:41805-00-9;4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide;4-Chloro-N-[[1-(dimethylamino)cyclohexyl]methyl]-benzamide;4-Chloro-N-((1-(dimethylamino)cyclohexyl)methyl)benzamide;4-chloro-N-[[1-(dimethylamino)cyclohexyl]methyl]benzamide;DTXSID301342408;STL203450;AKOS002326865;AH 8529;MCULE-9250830689;CS-0366719;NS00018230

Suppliers and Price of 4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:294.1498911
Heavy Atom Count:20
Complexity:318

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1(CCCCC1)CNC(=O)C2=CC=C(C=C2)Cl

Technology Process of 4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide

There total 4 articles about 4-chloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41806-09-1
1-aminomethyl‐1‐cyclohexanedimethylamine

: 122-01-0
4-chloro-benzoyl chloride

: 41805-00-9
4-Chlorbenzamidomethylcyclohexyldimethylamin

Guidance literature:: With triethylamine; In diethyl ether; at 20 ℃; for 16h;
DOI:10.1002/prp2.511

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 41805-00-9
4-Chlorbenzamidomethylcyclohexyldimethylamin

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 16 h / 20 °C

2: lithium aluminium tetrahydride / diethyl ether / 16 h / 20 °C

3: triethylamine / diethyl ether / 16 h / 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; triethylamine; In diethyl ether; water;
DOI:10.1002/prp2.511

Reference yield:

: 16499-30-2
1-(dimethylamino)cyclohexanecarbonitrile

: 41805-00-9
4-Chlorbenzamidomethylcyclohexyldimethylamin

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / diethyl ether / 16 h / 20 °C

2: triethylamine / diethyl ether / 16 h / 20 °C

With lithium aluminium tetrahydride; triethylamine; In diethyl ether;
DOI:10.1002/prp2.511