2,3-Dihydro-1-benzofuran-3-ylmethyl phenyl sulfide

Base Information

• Chemical Name: 2,3-Dihydro-1-benzofuran-3-ylmethyl phenyl sulfide
• CAS No.: 103304-48-9
• Molecular Formula: C15H14OS
• Molecular Weight: 242.342
• DSSTox Substance ID: DTXSID40546139
• Nikkaji Number: J3.229.210K
• Mol file: 103304-48-9.mol

Synonyms:103304-48-9;3-((phenylthio)methyl)-2,3-dihydrobenzofuran;2,3-dihydro-1-benzofuran-3-ylmethyl phenyl sulfide;DTXSID40546139;3-(phenylsulfanyl-methyl)-2,3-dihydro-benzofuran;3-[(Phenylsulfanyl)methyl]-2,3-dihydro-1-benzofuran

Chemical Property of 2,3-Dihydro-1-benzofuran-3-ylmethyl phenyl sulfide

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 242.07653624
• Heavy Atom Count: 17
• Complexity: 237

Purity/Quality:

99% ，98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C2=CC=CC=C2O1)CSC3=CC=CC=C3

Technology Process of 2,3-Dihydro-1-benzofuran-3-ylmethyl phenyl sulfide

There total 8 articles about 2,3-Dihydro-1-benzofuran-3-ylmethyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

diphenyldisulfane (882-33-7) → 3-<(thiophenyl)methyl>-2,3-dihydrobenzofuran (103304-48-9)

Guidance literature:

In dichloromethane; for 24h; Heating; Irradiation;

Reference yield: 57.0%

1-allyloxy-2-iodobenzene (24892-63-5) + thiophenol (108-98-5) → 3-<(thiophenyl)methyl>-2,3-dihydrobenzofuran (103304-48-9)

Guidance literature:

With copper(l) iodide; sodium t-butanolate; In acetonitrile; at 0 ℃; for 5h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/ja404050f

Reference yield: 53.0%

1-(2-(allyloxy)phenyl)-2-(tetrafluoro-λ5-boraneyl)diazene (25125-40-0) + thiophenol (108-98-5) → 3-<(thiophenyl)methyl>-2,3-dihydrobenzofuran (103304-48-9)

Guidance literature:

With copper; sodium hydride; In dimethyl sulfoxide; for 0.5h;

DOI:10.1021/ja00279a038

upstream raw materials:

1-(2-(allyloxy)phenyl)-2-(tetrafluoro-λ⁵-boraneyl)diazene

thiophenol

1-allyloxy-2-iodobenzene

diphenyldisulfane