Sodium (+)-(2S,3R)-E-3-phenyl oxirane-2-carboxylate

Base Information

• Chemical Name: Sodium (+)-(2S,3R)-E-3-phenyl oxirane-2-carboxylate
• CAS No.: 129939-42-0
• Molecular Formula: C₉H₇O₃*Na
• Molecular Weight: 186.143
• Mol file: 129939-42-0.mol

Synonyms:

Chemical Property of Sodium (+)-(2S,3R)-E-3-phenyl oxirane-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Sodium (+)-(2S,3R)-E-3-phenyl oxirane-2-carboxylate

There total 7 articles about Sodium (+)-(2S,3R)-E-3-phenyl oxirane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) → Sodium Z-3-phenyl oxirane-2-carboxylate (25957-39-5,41603-33-2,41603-36-5,54885-10-8,129939-41-9,129939-42-0,129939-43-1,129939-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / sodium ethoxide / diethyl ether / 18 h / Ambient temperature

2: 1.) sodium ethoxide, 2.) water / 1.) ethanol, 5 min

With water; sodium ethanolate; In diethyl ether;

DOI:10.1016/S0040-4020(01)82040-8

Reference yield:

benzaldehyde (100-52-7) → Sodium (+)-(2S,3R)-E-3-phenyl oxirane-2-carboxylate (129939-42-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / sodium ethoxide / diethyl ether / 18 h / Ambient temperature

2: 1.) sodium ethoxide, 2.) water / 1.) ethanol, 5 min

With water; sodium ethanolate; In diethyl ether;

DOI:10.1016/S0040-4020(01)82040-8

Reference yield:

ethyl cis-3-phenylglycidate (121-39-1,2272-49-3,2272-55-1,54276-44-7,56791-22-1,126060-73-9,130321-77-6,130321-78-7,130605-53-7) → Sodium Z-3-phenyl oxirane-2-carboxylate (25957-39-5,41603-33-2,41603-36-5,54885-10-8,129939-41-9,129939-42-0,129939-43-1,129939-44-2)

Guidance literature:

With water; sodium ethanolate; Yield given. Multistep reaction; 1.) ethanol, 5 min;

DOI:10.1016/S0040-4020(01)82040-8

upstream raw materials:

ethyl 3-phenylglycidate

ethyl cis-3-phenylglycidate

sodium (E)-3-phenylglycidate

benzaldehyde

Downstream raw materials:

Methyl (2R^*,3R^*)-3-phenyl-1H-aziridine-2-carboxylate

(2R,3R)-3-Phenyl-1-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-aziridine-2-carboxylic acid methyl ester

trans-(4S^*,5R^*)-2,2,2,4-Tetraphenyl-5-methoxycarbonyl-1,3,2-oxazaphospholidine

Methyl (2R,3S)-3-phenyl-1H-aziridine-2-carboxylate

Refernces