6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester

Base Information

• Chemical Name: 6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester
• CAS No.: 3022-90-0
• Molecular Formula: C₃₂H₄₆O₆S
• Molecular Weight: 558.78
• Mol file: 3022-90-0.mol

Synonyms:

Chemical Property of 6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester

There total 2 articles about 6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 6α-hydroxy-3-oxo-5β-cholan-24-oic acid (67733-54-4) → 6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester (3022-90-0)

Guidance literature:

beim Behandeln des hergestellten Methylesters mit Toluol-sulfonylchlorid-⁽⁴⁾ und Pyridin;

Reference yield:

→ Methyl-3-oxo-6α-tosyloxy-5β-cholanat (3022-90-0)

Guidance literature:

6-Hydroxy-Verb. IIIb, Tosylchlorid;

Reference yield:

2,4,6-trimethyl-pyridine (108-75-8) + 6α-(toluene-sulfonyl-(4)-oxy)-3-oxo-5β-cholanoic acid-(24)-methyl ester (3022-90-0) → methyl 3-oxo-4-cholenolate (1452-33-1)

Guidance literature:

upstream raw materials:

diazomethane

6α-hydroxy-3-oxo-5β-cholan-24-oic acid

Downstream raw materials:

methyl 3-oxo-4-cholenolate